Oligonucleotides with internal modifications

Guanosine modifications

7-Deaza-2'-deoxyguanosine (7-Deaza-2'-dG)

• Incorporation of 7-Deaza-2'-dG can reduce secondary structures
• Incorporation of 7-Deaza-2'-dG prevents formation of G-tetrades

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product	scale	amount	cat. no.	price/coupling
7-Deaza-2'-dG	0.05 µmol	5 nmol	5-0232-012	99.00 EUR
	0.20 µmol	25 nmol	5-0232-013	135.00 EUR
	1.00 µmol	100 nmol	5-0232-014	195.00 EUR

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8-Bromo-2'-deoxyguanosine (8-Br-2'-dG)

• Halogenated nucleosides are useful for crystallography
• Useful for probing the structure of Protein-RNA, Protein-DNA and DNA-RNA complexes in crosslinking experiments

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product	scale	amount	cat. no.	price/coupling
8-Br-2'-dG	0.05 µmol	5 nmol	5-0232-112	55.00 EUR
	0.20 µmol	25 nmol	5-0232-113	79.00 EUR
	1.00 µmol	100 nmol	5-0232-114	95.00 EUR

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see also "how to order"