Many mental incapacity issues are resulting from copy quantity variations, and, up to now, there have been no remedy choices examined for this class of ailments. MECP2 duplication syndrome (MDS) is without doubt one of the most typical genomic rearrangements in males and outcomes from duplications spanning the methyl-CpG binding protein 2 (MECP2) gene locus. We beforehand confirmed that antisense oligonucleotide (ASO) remedy can cut back MeCP2 protein quantity in an MDS mouse mannequin and reverse its illness options. This MDS mouse mannequin, nonetheless, carried one transgenic human allele and one mouse allele, with the latter being protected against human-specific MECP2-ASO focusing on.
As a result of MeCP2 is a dosage-sensitive protein, the ASO should be titrated such that the quantity of MeCP2 just isn’t lowered too far, which might trigger Rett syndrome. Due to this fact, we generated an “MECP2 humanized” MDS mannequin that carries two human MECP2 alleles and no mouse endogenous allele. Intracerebroventricular injection of the MECP2-ASO effectively down-regulated MeCP2 expression all through the mind in these mice. Furthermore, MECP2-ASO mitigated a number of behavioral deficits and restored expression of chosen MeCP2-regulated genes in a dose-dependent method with none toxicity. Central nervous system administration of MECP2-ASO is due to this fact nicely tolerated and useful on this mouse mannequin and offers a translatable strategy that might be possible for treating MDS.
A abstract of the important thing technological developments within the preparation of antibody-oligonucleotide conjugates (AOCs) and the distinct benefits and downsides of AOCs as novel therapeutics are offered. The deserves and demerits of the totally different approaches to conjugating oligonucleotides to antibodies, antibody fragments or different proteins, primarily from the angle of AOC purification and analytical characterizations, are assessed. The teachings realized from in vitro and in vivo research, particularly the findings associated to silencing, trafficking, and cytotoxicity of the conjugates, are additionally summarized.
Capillary electrophoresis-based methodology for screening of oligonucleotide aptamers
As a brand new molecular recognition aspect, oligonucleotide aptamer not solely has increased affinity and specificity to focus on molecules, but in addition has the benefits of broad recognition vary, in vitro synthesis and chemical stability in in contrast with standard antibodies. Since a form of screening methodology termed systematic evolution of ligands by exponential enrichment (SELEX) was reported, scientists have extensively researched on the methodology the best way to extremely and effectively display out aptamers from the library consisted of a lot of random oligonucleotides.
With none doubts, capillary electrophoresis-based screening methodologies, together with nonequilibrium capillary electrophoresis of equilibrium mixtures, equilibrium capillary electrophoresis of equilibrium mixtures, non-SELEX, ideal-filter capillary electrophoresis, capillary transient isotachophoresis, and many others., are most revolutionary. In contrast with standard SELEX, these capillary electrophoresis-based methodologies present the incomparable benefits such because the single-round screening of aptamers and the rise of profitable screening price. These methodology research on the screening strategy of aptamers are comprehensively commented on this assessment.
Extremely delicate quantitative protein profiling can play a key function within the early analysis of ailments, akin to autoimmune ailments and most cancers. We developed a modified protein-oligonucleotide conjugation methodology termed HaloTag-mediated barcoding, for quantifying protein molecules at a better sensitivity than standard protein quantification strategies. This novel and environment friendly conjugation methodology can be utilized to organize HaloTag-barcoded proteins utilizing a click on chemistry-based labeling method.
Right here, we describe the preparation of protein-DNA complexes and detection of protein-protein interactions which can be utilized in a HaloTag protein barcode assay to detect an antibody. The protocol contains procedures for making ready the ligand-oligonucleotide advanced, plasmid DNA preparation for protein expression, and preparation of the protein-oligonucleotide advanced.
Photothermal-triggered system for oligonucleotides supply from cationic gold nanorods floor: A molecular dynamic investigation
Bioconjugate gold-based nanostructures combining the plasmonic photothermal impact with photothermal-triggered DNA supply are interesting supplies for medical diagnostic and remedy for cell-based illness. On this examine, we exhibit using floor hybridization to organize DNA-modified gold nanorods for use as photo-delivery system for single stranded oligonucleotides. The as ready DNA modified gold nanorods have robust absorption bands within the seen and near-infrared areas by which the absorbed mild by means of photothermal impact, induces a floor temperature growing as much as the melting temperature with consequent DNA launch.
No evident DNA launch was noticed under the melting temperature. The experimental information had been supported by molecular dynamic simulation investigation, exhibiting the kinetics side of dsDNA de-hybridization at gold nanorods floor at temperature under (298 Okay) and above (333 Okay) the melting temperature of sequence investigated. We exhibit that the cationic costs of surfactant, localized at nanorods floor, induce a outstanding de-hybridization of strands DNA, as confirmed by an growing of hybridization enthalpy worth of about 7 kcal/mol and by a sooner de-hybridization course of, respect the mannequin of gold nanorods with out constructive costs.
Fascin (FSCN) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB757Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Fascin (FSCN). This antibody is labeled with FITC. |
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Neprilysin (NEP) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB785Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Neprilysin (NEP). This antibody is labeled with FITC. |
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Neprilysin (NEP) Polyclonal Antibody (Rat), FITC |
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| 4-PAB785Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Neprilysin (NEP). This antibody is labeled with FITC. |
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Neprilysin (NEP) Polyclonal Antibody (Rat), FITC |
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| 4-PAB785Ra02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Neprilysin (NEP). This antibody is labeled with FITC. |
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Arginine (Arg) Polyclonal Antibody (General), FITC |
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| 4-PAB938Ge01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against General Arginine (Arg). This antibody is labeled with FITC. |
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Epiregulin (EREG) Polyclonal Antibody (Rat), FITC |
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| 4-PAB945Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Epiregulin (EREG). This antibody is labeled with FITC. |
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Acrosin (ACR) Polyclonal Antibody (Rat), FITC |
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| 4-PAB947Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Acrosin (ACR). This antibody is labeled with FITC. |
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Hepcidin (Hepc) Polyclonal Antibody (Bovine), FITC |
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| 4-PAB979Bo01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Bovine Hepcidin (Hepc). This antibody is labeled with FITC. |
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Hepcidin (Hepc) Polyclonal Antibody (Human), FITC |
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| 4-PAB979Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Hepcidin (Hepc). This antibody is labeled with FITC. |
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Hepcidin (Hepc) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB979Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Hepcidin (Hepc). This antibody is labeled with FITC. |
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Hepcidin (Hepc) Polyclonal Antibody (Pig), FITC |
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| 4-PAB979Po01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Pig Hepcidin (Hepc). This antibody is labeled with FITC. |
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Hepcidin (Hepc) Polyclonal Antibody (Rat), FITC |
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| 4-PAB979Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Hepcidin (Hepc). This antibody is labeled with FITC. |
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Hemopexin (HPX) Polyclonal Antibody (Human), FITC |
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| 4-PAB986Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Hemopexin (HPX). This antibody is labeled with FITC. |
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Hemopexin (HPX) Polyclonal Antibody (Human), FITC |
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| 4-PAB986Hu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Hemopexin (HPX). This antibody is labeled with FITC. |
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Hemopexin (HPX) Polyclonal Antibody (Rat), FITC |
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| 4-PAB986Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Hemopexin (HPX). This antibody is labeled with FITC. |
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Hemopexin (HPX) Polyclonal Antibody (Rat), FITC |
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| 4-PAB986Ra02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Hemopexin (HPX). This antibody is labeled with FITC. |
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Hemojuvelin (HJV) Polyclonal Antibody (Human), FITC |
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| 4-PAB995Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Hemojuvelin (HJV). This antibody is labeled with FITC. |
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Lipopolysaccharide (LPS) Polyclonal Antibody (General), FITC |
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| 4-PAB526Ge01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against General Lipopolysaccharide (LPS). This antibody is labeled with FITC. |
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Palladin (PALLD) Polyclonal Antibody (Human), FITC |
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| 4-PAB590Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Palladin (PALLD). This antibody is labeled with FITC. |
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Neuraminidase (NEU) Polyclonal Antibody (Human), FITC |
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| 4-PAB611Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuraminidase (NEU). This antibody is labeled with FITC. |
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Myostatin (MSTN) Polyclonal Antibody (Bovine), FITC |
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| 4-PAB653Bo01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Bovine Myostatin (MSTN). This antibody is labeled with FITC. |
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Myostatin (MSTN) Polyclonal Antibody (Human), FITC |
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| 4-PAB653Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Myostatin (MSTN). This antibody is labeled with FITC. |
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Myostatin (MSTN) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB653Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Myostatin (MSTN). This antibody is labeled with FITC. |
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Myostatin (MSTN) Polyclonal Antibody (Pig), FITC |
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| 4-PAB653Po01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Pig Myostatin (MSTN). This antibody is labeled with FITC. |
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Myostatin (MSTN) Polyclonal Antibody (Human), FITC |
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| 4-PAB653Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Myostatin (MSTN). This antibody is labeled with FITC. |
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Prekallikrein (PK) Polyclonal Antibody (Human), FITC |
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| 4-PAB801Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Prekallikrein (PK). This antibody is labeled with FITC. |
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Versican (VS) Polyclonal Antibody (Human), FITC |
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| 4-PAB817Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Versican (VS). This antibody is labeled with FITC. |
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Versican (VS) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB817Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Versican (VS). This antibody is labeled with FITC. |
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Vinculin (VCL) Polyclonal Antibody (Human), FITC |
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| 4-PAB839Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Vinculin (VCL). This antibody is labeled with FITC. |
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Paxillin (Pax) Polyclonal Antibody (Human), FITC |
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| 4-PAB844Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Paxillin (Pax). This antibody is labeled with FITC. |
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Nitrotyrosine (NT) Polyclonal Antibody (General), FITC |
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| 4-PAB863Ge01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against General Nitrotyrosine (NT). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Bovine), FITC |
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| 4-PAB908Bo01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Bovine Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Human), FITC |
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| 4-PAB908Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Human), FITC |
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| 4-PAB908Hu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Human), FITC |
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| 4-PAB908Hu03-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB908Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB908Mu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Rat), FITC |
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| 4-PAB908Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Aggrecan (AGC). This antibody is labeled with FITC. |
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Aggrecan (AGC) Polyclonal Antibody (Rat), FITC |
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| 4-PAB908Ra02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Aggrecan (AGC). This antibody is labeled with FITC. |
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Hemoglobin (HB) Polyclonal Antibody (Bovine), FITC |
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| 4-PAB409Bo01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Bovine Hemoglobin (HB). This antibody is labeled with FITC. |
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Hemoglobin (HB) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB409Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Hemoglobin (HB). This antibody is labeled with FITC. |
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Hemoglobin (HB) Polyclonal Antibody (Pig), FITC |
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| 4-PAB409Po01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Pig Hemoglobin (HB). This antibody is labeled with FITC. |
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Hemoglobin (HB) Polyclonal Antibody (Rabbit), FITC |
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| 4-PAB409Rb51-FITC | Cloud-Clone |
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Description: A Guinea polyclonal antibody against Rabbit Hemoglobin (HB). This antibody is labeled with FITC. |
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Acetylcholinesterase (AchE) Polyclonal Antibody (Human), FITC |
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| 4-PAB447Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Acetylcholinesterase (AchE). This antibody is labeled with FITC. |
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Acetylcholinesterase (AchE) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB447Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Acetylcholinesterase (AchE). This antibody is labeled with FITC. |
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Acetylcholinesterase (AchE) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB447Mu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Acetylcholinesterase (AchE). This antibody is labeled with FITC. |
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Acetylcholinesterase (AchE) Polyclonal Antibody (Rat), FITC |
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| 4-PAB447Ra02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Acetylcholinesterase (AchE). This antibody is labeled with FITC. |
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Ovalbumin (OVA) Polyclonal Antibody (Chicken), FITC |
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| 4-PAB459Ge01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Chicken Ovalbumin (OVA). This antibody is labeled with FITC. |
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Fibromodulin (FMOD) Polyclonal Antibody (Human), FITC |
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| 4-PAB494Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Fibromodulin (FMOD). This antibody is labeled with FITC. |
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Fibromodulin (FMOD) Polyclonal Antibody (Rat), FITC |
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| 4-PAB494Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Fibromodulin (FMOD). This antibody is labeled with FITC. |
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Lumican (LUM) Polyclonal Antibody (Human), FITC |
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| 4-PAB496Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lumican (LUM). This antibody is labeled with FITC. |
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Lumican (LUM) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB496Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Lumican (LUM). This antibody is labeled with FITC. |
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Dystrophin (DMD) Polyclonal Antibody (Human), FITC |
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| 4-PAB503Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Dystrophin (DMD). This antibody is labeled with FITC. |
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Dystrophin (DMD) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB503Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Dystrophin (DMD). This antibody is labeled with FITC. |
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Caldesmon (CALD) Polyclonal Antibody (Human), FITC |
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| 4-PAB324Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Caldesmon (CALD). This antibody is labeled with FITC. |
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Involucrin (iNV) Polyclonal Antibody (Human), FITC |
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| 4-PAB331Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Involucrin (iNV). This antibody is labeled with FITC. |
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Involucrin (iNV) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB331Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Involucrin (iNV). This antibody is labeled with FITC. |
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Involucrin (iNV) Polyclonal Antibody (Rat), FITC |
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| 4-PAB331Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Involucrin (iNV). This antibody is labeled with FITC. |
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Involucrin (iNV) Polyclonal Antibody (Rat), FITC |
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| 4-PAB331Ra02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Involucrin (iNV). This antibody is labeled with FITC. |
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Protectin (CD59) Polyclonal Antibody (Human), FITC |
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| 4-PAB336Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Protectin (CD59). This antibody is labeled with FITC. |
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Protectin (CD59) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB336Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Protectin (CD59). This antibody is labeled with FITC. |
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Protectin (CD59) Polyclonal Antibody (Pig), FITC |
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| 4-PAB336Po01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Pig Protectin (CD59). This antibody is labeled with FITC. |
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Protectin (CD59) Polyclonal Antibody (Rat), FITC |
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| 4-PAB336Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Protectin (CD59). This antibody is labeled with FITC. |
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Protectin (CD59) Polyclonal Antibody (Human), FITC |
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| 4-PAB336Si01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Protectin (CD59). This antibody is labeled with FITC. |
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Elastin (ELN) Polyclonal Antibody (Human), FITC |
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| 4-PAB337Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Elastin (ELN). This antibody is labeled with FITC. |
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Elastin (ELN) Polyclonal Antibody (Human), FITC |
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| 4-PAB337Hu08-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Elastin (ELN). This antibody is labeled with FITC. |
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Elastin (ELN) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB337Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Elastin (ELN). This antibody is labeled with FITC. |
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Prolylcarboxypeptidase (PRCP) Polyclonal Antibody (Human), FITC |
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| 4-PAB253Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Prolylcarboxypeptidase (PRCP). This antibody is labeled with FITC. |
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Prolylcarboxypeptidase (PRCP) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB253Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Prolylcarboxypeptidase (PRCP). This antibody is labeled with FITC. |
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Prolylcarboxypeptidase (PRCP) Polyclonal Antibody (Rat), FITC |
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| 4-PAB253Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Prolylcarboxypeptidase (PRCP). This antibody is labeled with FITC. |
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Angiostatin (ANG) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB254Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiostatin (ANG). This antibody is labeled with FITC. |
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Angiostatin (ANG) Polyclonal Antibody (Rat), FITC |
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| 4-PAB254Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Angiostatin (ANG). This antibody is labeled with FITC. |
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Glucagon (GC) Polyclonal Antibody (Human), FITC |
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| 4-PAB266Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Glucagon (GC). This antibody is labeled with FITC. |
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Glucagon (GC) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB266Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Glucagon (GC). This antibody is labeled with FITC. |
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Glucagon (GC) Polyclonal Antibody (Rat), FITC |
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| 4-PAB266Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Glucagon (GC). This antibody is labeled with FITC. |
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Agrin (AGRN) Polyclonal Antibody (Human), FITC |
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| 4-PAB303Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Agrin (AGRN). This antibody is labeled with FITC. |
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Agrin (AGRN) Polyclonal Antibody (Human), FITC |
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| 4-PAB303Hu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Agrin (AGRN). This antibody is labeled with FITC. |
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Agrin (AGRN) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB303Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Agrin (AGRN). This antibody is labeled with FITC. |
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Agrin (AGRN) Polyclonal Antibody (Rat), FITC |
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| 4-PAB303Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Agrin (AGRN). This antibody is labeled with FITC. |
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Pleiotrophin (PTN) Polyclonal Antibody (Bovine), FITC |
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| 4-PAB309Bo01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Bovine Pleiotrophin (PTN). This antibody is labeled with FITC. |
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Pleiotrophin (PTN) Polyclonal Antibody (Human), FITC |
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| 4-PAB309Hu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Pleiotrophin (PTN). This antibody is labeled with FITC. |
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Pleiotrophin (PTN) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB309Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Pleiotrophin (PTN). This antibody is labeled with FITC. |
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Proopiomelanocortin (POMC) Polyclonal Antibody (Human), FITC |
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| 4-PAB311Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Proopiomelanocortin (POMC). This antibody is labeled with FITC. |
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Proopiomelanocortin (POMC) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB311Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Proopiomelanocortin (POMC). This antibody is labeled with FITC. |
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Proopiomelanocortin (POMC) Polyclonal Antibody (Rat), FITC |
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| 4-PAB311Ra01-FITC | Cloud-Clone |
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|
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Description: A Rabbit polyclonal antibody against Rat Proopiomelanocortin (POMC). This antibody is labeled with FITC. |
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Lysozyme (LZM) Polyclonal Antibody (Bovine), FITC |
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| 4-PAB193Bo01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Bovine Lysozyme (LZM). This antibody is labeled with FITC. |
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Lysozyme (LZM) Polyclonal Antibody (Chicken), FITC |
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| 4-PAB193Ga01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Chicken Lysozyme (LZM). This antibody is labeled with FITC. |
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Lysozyme (LZM) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB193Mu01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Mouse Lysozyme (LZM). This antibody is labeled with FITC. |
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Lysozyme (LZM) Polyclonal Antibody (Rat), FITC |
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| 4-PAB193Ra01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Rat Lysozyme (LZM). This antibody is labeled with FITC. |
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Neurotensin (NT) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB203Mu01-FITC | Cloud-Clone |
|
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Description: A Rabbit polyclonal antibody against Mouse Neurotensin (NT). This antibody is labeled with FITC. |
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Neurotensin (NT) Polyclonal Antibody (Rat), FITC |
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| 4-PAB203Ra01-FITC | Cloud-Clone |
|
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Description: A Rabbit polyclonal antibody against Rat Neurotensin (NT). This antibody is labeled with FITC. |
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Relaxin (RLN) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB216Mu01-FITC | Cloud-Clone |
|
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Description: A Rabbit polyclonal antibody against Mouse Relaxin (RLN). This antibody is labeled with FITC. |
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Relaxin (RLN) Polyclonal Antibody (Rat), FITC |
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| 4-PAB216Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Relaxin (RLN). This antibody is labeled with FITC. |
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Hyaluronidase (HAase) Polyclonal Antibody (Human), FITC |
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| 4-PAB217Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Hyaluronidase (HAase). This antibody is labeled with FITC. |
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Gastrin (GT) Polyclonal Antibody (Dog), FITC |
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| 4-PAB224Ca01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Dog Gastrin (GT). This antibody is labeled with FITC. |
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Gastrin (GT) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB224Mu01-FITC | Cloud-Clone |
|
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Description: A Rabbit polyclonal antibody against Mouse Gastrin (GT). This antibody is labeled with FITC. |
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Gastrin (GT) Polyclonal Antibody (Rat), FITC |
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| 4-PAB224Ra01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Rat Gastrin (GT). This antibody is labeled with FITC. |
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Plasminogen (Plg) Polyclonal Antibody (Human), FITC |
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| 4-PAB236Hu02-FITC | Cloud-Clone |
|
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Description: A Rabbit polyclonal antibody against Human Plasminogen (Plg). This antibody is labeled with FITC. |
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Plasminogen (Plg) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB236Mu01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Mouse Plasminogen (Plg). This antibody is labeled with FITC. |
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Plasminogen (Plg) Polyclonal Antibody (Rat), FITC |
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| 4-PAB236Ra01-FITC | Cloud-Clone |
|
|
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Description: A Rabbit polyclonal antibody against Rat Plasminogen (Plg). This antibody is labeled with FITC. |
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Motilin (MTL) Monoclonal Antibody (Human), FITC |
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| 4-MAA575Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Motilin (MTL). This antibody is labeled with FITC. |
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Somatostatin (SST) Monoclonal Antibody (Mouse), FITC |
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| 4-MAA592Mu21-FITC | Cloud-Clone |
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Description: A Rat monoclonal antibody against Mouse Somatostatin (SST). This antibody is labeled with FITC. |
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Myeloperoxidase (MPO) Monoclonal Antibody (Bovine), FITC |
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| 4-MAA601Bo21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Bovine Myeloperoxidase (MPO). This antibody is labeled with FITC. |
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Myeloperoxidase (MPO) Monoclonal Antibody (Human), FITC |
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| 4-MAA601Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Myeloperoxidase (MPO). This antibody is labeled with FITC. |
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Adiponectin (ADP) Monoclonal Antibody (Rat), FITC |
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| 4-MAA605Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Adiponectin (ADP). This antibody is labeled with FITC. |
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Midkine (MK) Monoclonal Antibody (Human), FITC |
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| 4-MAA631Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Midkine (MK). This antibody is labeled with FITC. |
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Pepsin (PP) Monoclonal Antibody (Human), FITC |
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| 4-MAA632Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with FITC. |
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Visfatin (VF) Monoclonal Antibody (Human), FITC |
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| 4-MAA638Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Visfatin (VF). This antibody is labeled with FITC. |
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Visfatin (VF) Monoclonal Antibody (Rat), FITC |
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| 4-MAA638Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Visfatin (VF). This antibody is labeled with FITC. |
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Procalcitonin (PCT) Monoclonal Antibody (Human), FITC |
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| 4-MAA689Hu28-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Procalcitonin (PCT). This antibody is labeled with FITC. |
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Thioredoxin (Trx) Monoclonal Antibody (Human), FITC |
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| 4-MAA702Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Thioredoxin (Trx). This antibody is labeled with FITC. |
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Heparanase (HPA) Monoclonal Antibody (Human), FITC |
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| 4-MAA711Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Heparanase (HPA). This antibody is labeled with FITC. |
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Transthyretin (TTR) Monoclonal Antibody (Human), FITC |
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| 4-MAA726Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Transthyretin (TTR). This antibody is labeled with FITC. |
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Lactoferrin (LTF) Monoclonal Antibody (Human), FITC |
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| 4-MAA780Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lactoferrin (LTF). This antibody is labeled with FITC. |
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Angiotensinogen (AGT) Monoclonal Antibody (Rat), FITC |
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| 4-MAA797Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Angiotensinogen (AGT). This antibody is labeled with FITC. |
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Amylin Monoclonal Antibody (Pan-species), FITC |
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| 4-MAA812Ge28-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pan-species Amylin. This antibody is labeled with FITC. |
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Prolactin (PRL) Monoclonal Antibody (Human), FITC |
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| 4-MAA846Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Prolactin (PRL). This antibody is labeled with FITC. |
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Resistin (RETN) Monoclonal Antibody (Human), FITC |
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| 4-MAA847Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Resistin (RETN). This antibody is labeled with FITC. |
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Resistin (RETN) Monoclonal Antibody (Mouse), FITC |
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| 4-MAA847Mu21-FITC | Cloud-Clone |
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Description: A Rat monoclonal antibody against Mouse Resistin (RETN). This antibody is labeled with FITC. |
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Renin (REN) Monoclonal Antibody (Rat), FITC |
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| 4-MAA889Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Renin (REN). This antibody is labeled with FITC. |
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Ceruloplasmin (CP) Monoclonal Antibody (Human), FITC |
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| 4-MAA909Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Ceruloplasmin (CP). This antibody is labeled with FITC. |
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Ceruloplasmin (CP) Monoclonal Antibody (Human), FITC |
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| 4-MAA909Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Ceruloplasmin (CP). This antibody is labeled with FITC. |
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Ceruloplasmin (CP) Monoclonal Antibody (Rat), FITC |
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| 4-MAA909Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Ceruloplasmin (CP). This antibody is labeled with FITC. |
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Histamine (HA) Monoclonal Antibody (General), FITC |
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| 4-MAA927Ge21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against General Histamine (HA). This antibody is labeled with FITC. |
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Nephrin (NPHN) Monoclonal Antibody (Human), FITC |
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| 4-MAA937Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Nephrin (NPHN). This antibody is labeled with FITC. |
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Nephrin (NPHN) Monoclonal Antibody (Human), FITC |
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| 4-MAA937Hu22-FITC | Cloud-Clone |
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|
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Description: A Mouse monoclonal antibody against Human Nephrin (NPHN). This antibody is labeled with FITC. |
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Nephrin (NPHN) Monoclonal Antibody (Rat), FITC |
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| 4-MAA937Ra21-FITC | Cloud-Clone |
|
|
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Description: A Mouse monoclonal antibody against Rat Nephrin (NPHN). This antibody is labeled with FITC. |
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Podocin (PDCN) Monoclonal Antibody (Human), FITC |
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| 4-MAA938Hu22-FITC | Cloud-Clone |
|
|
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Description: A Mouse monoclonal antibody against Human Podocin (PDCN). This antibody is labeled with FITC. |
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Chemerin (CHEM) Monoclonal Antibody (Human), FITC |
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| 4-MAA945Hu22-FITC | Cloud-Clone |
|
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Description: A Mouse monoclonal antibody against Human Chemerin (CHEM). This antibody is labeled with FITC. |
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Endoglin (ENG) Monoclonal Antibody (Human), FITC |
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| 4-MAA980Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Endoglin (ENG). This antibody is labeled with FITC. |
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Albumin (ALB) Monoclonal Antibody (Human), FITC |
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| 4-MAB028Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Albumin (ALB). This antibody is labeled with FITC. |
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Tryptase (TPS) Monoclonal Antibody (Human), FITC |
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| 4-MAB070Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Tryptase (TPS). This antibody is labeled with FITC. |
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Tryptase (TPS) Monoclonal Antibody (Human), FITC |
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| 4-MAB070Hu22-FITC | Cloud-Clone |
|
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Description: A Mouse monoclonal antibody against Human Tryptase (TPS). This antibody is labeled with FITC. |
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Tryptase (TPS) Monoclonal Antibody (Human), FITC |
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| 4-MAB070Hu24-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Tryptase (TPS). This antibody is labeled with FITC. |
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Tryptase (TPS) Monoclonal Antibody (Human), FITC |
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| 4-MAB070Hu26-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Tryptase (TPS). This antibody is labeled with FITC. |
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Arginase (ARG) Monoclonal Antibody (Human), FITC |
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| 4-MAB120Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Arginase (ARG). This antibody is labeled with FITC. |
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Antithrombin (AT) Monoclonal Antibody (Human), FITC |
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| 4-MAC313Hu21-FITC | Cloud-Clone |
|
|
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Description: A Mouse monoclonal antibody against Human Antithrombin (AT). This antibody is labeled with FITC. |
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Antithrombin (AT) Monoclonal Antibody (Human), FITC |
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| 4-MAC313Hu22-FITC | Cloud-Clone |
|
|
|
Description: A Mouse monoclonal antibody against Human Antithrombin (AT). This antibody is labeled with FITC. |
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Catalase (CAT) Monoclonal Antibody (Human), FITC |
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| 4-MAC418Hu22-FITC | Cloud-Clone |
|
|
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Description: A Mouse monoclonal antibody against Human Catalase (CAT). This antibody is labeled with FITC. |
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These information had been corroborated by the growing of the basis imply sq. deviation worth (about 4.Four Å, calculated at 333 Okay) indicating that the presence of cationic headgroup at gold floor induce separation of the double strand. This discovering information paving the way in which for the event of nanostructured materials for photothermal-triggered supply methods of DNA for gene remedy software. Approval of nusinersen, an intrathecally administered antisense oligonucleotide, for the remedy of 5q-spinal muscular atrophy (SMA) marked the start of a brand new therapeutic period in neurological ailments.