Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome

Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome

Many mental incapacity issues are resulting from copy quantity variations, and, up to now, there have been no remedy choices examined for this class of ailments. MECP2 duplication syndrome (MDS) is without doubt one of the most typical genomic rearrangements in males and outcomes from duplications spanning the methyl-CpG binding protein 2 (MECP2) gene locus. We beforehand confirmed that antisense oligonucleotide (ASO) remedy can cut back MeCP2 protein quantity in an MDS mouse mannequin and reverse its illness options. This MDS mouse mannequin, nonetheless, carried one transgenic human allele and one mouse allele, with the latter being protected against human-specific MECP2-ASO focusing on.

As a result of MeCP2 is a dosage-sensitive protein, the ASO should be titrated such that the quantity of MeCP2 just isn’t lowered too far, which might trigger Rett syndrome. Due to this fact, we generated an “MECP2 humanized” MDS mannequin that carries two human MECP2 alleles and no mouse endogenous allele. Intracerebroventricular injection of the MECP2-ASO effectively down-regulated MeCP2 expression all through the mind in these mice. Furthermore, MECP2-ASO mitigated a number of behavioral deficits and restored expression of chosen MeCP2-regulated genes in a dose-dependent method with none toxicity. Central nervous system administration of MECP2-ASO is due to this fact nicely tolerated and useful on this mouse mannequin and offers a translatable strategy that might be possible for treating MDS.

A abstract of the important thing technological developments within the preparation of antibody-oligonucleotide conjugates (AOCs) and the distinct benefits and downsides of AOCs as novel therapeutics are offered. The deserves and demerits of the totally different approaches to conjugating oligonucleotides to antibodies, antibody fragments or different proteins, primarily from the angle of AOC purification and analytical characterizations, are assessed. The teachings realized from in vitro and in vivo research, particularly the findings associated to silencing, trafficking, and cytotoxicity of the conjugates, are additionally summarized.

Capillary electrophoresis-based methodology for screening of oligonucleotide aptamers

As a brand new molecular recognition aspect, oligonucleotide aptamer not solely has increased affinity and specificity to focus on molecules, but in addition has the benefits of broad recognition vary, in vitro synthesis and chemical stability in in contrast with standard antibodies. Since a form of screening methodology termed systematic evolution of ligands by exponential enrichment (SELEX) was reported, scientists have extensively researched on the methodology the best way to extremely and effectively display out aptamers from the library consisted of a lot of random oligonucleotides.

With none doubts, capillary electrophoresis-based screening methodologies, together with nonequilibrium capillary electrophoresis of equilibrium mixtures, equilibrium capillary electrophoresis of equilibrium mixtures, non-SELEX, ideal-filter capillary electrophoresis, capillary transient isotachophoresis, and many others., are most revolutionary. In contrast with standard SELEX, these capillary electrophoresis-based methodologies present the incomparable benefits such because the single-round screening of aptamers and the rise of profitable screening price. These methodology research on the screening strategy of aptamers are comprehensively commented on this assessment.

Extremely delicate quantitative protein profiling can play a key function within the early analysis of ailments, akin to autoimmune ailments and most cancers. We developed a modified protein-oligonucleotide conjugation methodology termed HaloTag-mediated barcoding, for quantifying protein molecules at a better sensitivity than standard protein quantification strategies. This novel and environment friendly conjugation methodology can be utilized to organize HaloTag-barcoded proteins utilizing a click on chemistry-based labeling method.

Right here, we describe the preparation of protein-DNA complexes and detection of protein-protein interactions which can be utilized in a HaloTag protein barcode assay to detect an antibody. The protocol contains procedures for making ready the ligand-oligonucleotide advanced, plasmid DNA preparation for protein expression, and preparation of the protein-oligonucleotide advanced.

Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome

Photothermal-triggered system for oligonucleotides supply from cationic gold nanorods floor: A molecular dynamic investigation

Bioconjugate gold-based nanostructures combining the plasmonic photothermal impact with photothermal-triggered DNA supply are interesting supplies for medical diagnostic and remedy for cell-based illness. On this examine, we exhibit using floor hybridization to organize DNA-modified gold nanorods for use as photo-delivery system for single stranded oligonucleotides. The as ready DNA modified gold nanorods have robust absorption bands within the seen and near-infrared areas by which the absorbed mild by means of photothermal impact, induces a floor temperature growing as much as the melting temperature with consequent DNA launch.

No evident DNA launch was noticed under the melting temperature. The experimental information had been supported by molecular dynamic simulation investigation, exhibiting the kinetics side of dsDNA de-hybridization at gold nanorods floor at temperature under (298 Okay) and above (333 Okay) the melting temperature of sequence investigated. We exhibit that the cationic costs of surfactant, localized at nanorods floor, induce a outstanding de-hybridization of strands DNA, as confirmed by an growing of hybridization enthalpy worth of about 7 kcal/mol and by a sooner de-hybridization course of, respect the mannequin of gold nanorods with out constructive costs.

FITC Conjugated Protein G

BA1121-1 1ml
EUR 364.8

P Antibody, FITC conjugated

1-CSB-PA768100LC01VBH
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Description: A polyclonal antibody against P. Recognizes P from Vesicular stomatitis Indiana virus. This antibody is FITC conjugated. Tested in the following application: ELISA

L Antibody, FITC conjugated

1-CSB-PA806333LC01VBE
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Description: A polyclonal antibody against L. Recognizes L from Vesicular stomatitis Indiana virus. This antibody is FITC conjugated. Tested in the following application: ELISA

B1 Antibody, FITC conjugated

1-CSB-PA882501LC01HKA
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Description: A polyclonal antibody against B1. Recognizes B1 from Human herpesvirus 6B. This antibody is FITC conjugated. Tested in the following application: ELISA

NP Antibody, FITC conjugated

1-CSB-PA841983HC01RCI
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Description: A polyclonal antibody against NP. Recognizes NP from Reston ebolavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

X Antibody, FITC conjugated

1-CSB-PA865559LC01HEO
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Description: A polyclonal antibody against X. Recognizes X from Hepatitis B virus genotype D subtype ayw. This antibody is FITC conjugated. Tested in the following application: ELISA

TH Antibody, FITC conjugated

1-CSB-PA023470LC01HU
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Description: A polyclonal antibody against TH. Recognizes TH from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

TK Antibody, FITC conjugated

1-CSB-PA023577HC01HWY
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Description: A polyclonal antibody against TK. Recognizes TK from Human herpesvirus 1. This antibody is FITC conjugated. Tested in the following application: ELISA

PC Antibody, FITC conjugated

1-CSB-PA017511LC01HU
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Description: A polyclonal antibody against PC. Recognizes PC from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

MB Antibody, FITC conjugated

1-CSB-PA013529YC01HU
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Description: A polyclonal antibody against MB. Recognizes MB from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

XG Antibody, FITC conjugated

1-CSB-PA026190LC01HU
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Description: A polyclonal antibody against XG. Recognizes XG from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

C5 Antibody, FITC conjugated

1-CSB-PA003995LC01HU
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Description: A polyclonal antibody against C5. Recognizes C5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

C5 Antibody, FITC conjugated

1-CSB-PA003995YC01PI
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Description: A polyclonal antibody against C5. Recognizes C5 from Pig. This antibody is FITC conjugated. Tested in the following application: ELISA

C6 Antibody, FITC conjugated

1-CSB-PA004036LC01HU
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Description: A polyclonal antibody against C6. Recognizes C6 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

C9 Antibody, FITC conjugated

1-CSB-PA004259LC01HU
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Description: A polyclonal antibody against C9. Recognizes C9 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Tf Antibody, FITC conjugated

1-CSB-PA00470G0Rb
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Description: A polyclonal antibody against Tf. Recognizes Tf from Rat. This antibody is FITC conjugated. Tested in the following application: ELISA

CS Antibody, FITC conjugated

1-CSB-PA006031LC01HU
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Description: A polyclonal antibody against CS. Recognizes CS from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

F2 Antibody, FITC conjugated

1-CSB-PA007923LC01HU
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Description: A polyclonal antibody against F2. Recognizes F2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

F3 Antibody, FITC conjugated

1-CSB-PA007928LC01HU
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Description: A polyclonal antibody against F3. Recognizes F3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

F5 Antibody, FITC conjugated

1-CSB-PA007929HC01HU
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Description: A polyclonal antibody against F5. Recognizes F5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

F7 Antibody, FITC conjugated

1-CSB-PA007930HC01HU
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Description: A polyclonal antibody against F7. Recognizes F7 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

F8 Antibody, FITC conjugated

1-CSB-PA007932LC01HU
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Description: A polyclonal antibody against F8. Recognizes F8 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

F9 Antibody, FITC conjugated

1-CSB-PA007936LC01HU
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Description: A polyclonal antibody against F9. Recognizes F9 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

FH Antibody, FITC conjugated

1-CSB-PA008659LC01HU
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Description: A polyclonal antibody against FH. Recognizes FH from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

KY Antibody, FITC conjugated

1-CSB-PA012702LC01HU
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Description: A polyclonal antibody against KY. Recognizes KY from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AR Antibody, FITC conjugated

1-CSB-PA05979C0Rb
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Description: A polyclonal antibody against AR. Recognizes AR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NS Antibody, FITC conjugated

1-CSB-PA604972LC01IER
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Description: A polyclonal antibody against NS. Recognizes NS from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

HA Antibody, FITC conjugated

1-CSB-PA607773LC01IER
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Description: A polyclonal antibody against HA. Recognizes HA from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

gD Antibody, FITC conjugated

1-CSB-PA18929C0Rb
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Description: A polyclonal antibody against gD. Recognizes gD from Human herpesvirus 1. This antibody is FITC conjugated. Tested in the following application: ELISA

HA Antibody, FITC conjugated

1-CSB-PA18939C0Rb
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Description: A polyclonal antibody against HA. Recognizes HA from Influenza A virus(H7N9). This antibody is FITC conjugated. Tested in the following application: ELISA

th Antibody, FITC conjugated

1-CSB-PA24419C0Rb
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Description: A polyclonal antibody against th. Recognizes th from Zebrafish. This antibody is FITC conjugated. Tested in the following application: ELISA

GK Antibody, FITC conjugated

1-CSB-PA300097LC01HU
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Description: A polyclonal antibody against GK. Recognizes GK from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

IX Antibody, FITC conjugated

1-CSB-PA301675LC01ECY
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Description: A polyclonal antibody against IX. Recognizes IX from Enterobacteria phage M13. This antibody is FITC conjugated. Tested in the following application: ELISA

P Antibody, FITC conjugated

1-CSB-PA303154LC01RAH
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Description: A polyclonal antibody against P. Recognizes P from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

GP Antibody, FITC conjugated

1-CSB-PA308957LC01ZAA
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Description: A polyclonal antibody against GP. Recognizes GP from Zaire ebolavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

GP Antibody, FITC conjugated

1-CSB-PA310843LC01ZAA
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Description: A polyclonal antibody against GP. Recognizes GP from Zaire ebolavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

GP Antibody, FITC conjugated

1-CSB-PA314099LC01ZAT
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Description: A polyclonal antibody against GP. Recognizes GP from Zaire ebolavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

F Antibody, FITC conjugated

1-CSB-PA318261LC01CCQ
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Description: A polyclonal antibody against F. Recognizes F from Canine distemper virus. This antibody is FITC conjugated. Tested in the following application: ELISA

N Antibody, FITC conjugated

1-CSB-PA318401LC01LNP
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Description: A polyclonal antibody against N. Recognizes N from Lassa virus. This antibody is FITC conjugated. Tested in the following application: ELISA

N Antibody, FITC conjugated

1-CSB-PA318492LC01JAM
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Description: A polyclonal antibody against N. Recognizes N from Junin mammarenavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

gH Antibody, FITC conjugated

1-CSB-PA319015LC01HWV
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Description: A polyclonal antibody against gH. Recognizes gH from Human cytomegalovirus. This antibody is FITC conjugated. Tested in the following application: ELISA

N Antibody, FITC conjugated

1-CSB-PA321352LC01RAI
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Description: A polyclonal antibody against N. Recognizes N from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

N Antibody, FITC conjugated

1-CSB-PA321352YC01RAI
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Description: A polyclonal antibody against N. Recognizes N from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

M Antibody, FITC conjugated

1-CSB-PA322192LC01RAI
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Description: A polyclonal antibody against M. Recognizes M from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

S Antibody, FITC conjugated

1-CSB-PA322803LC01BJK
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Description: A polyclonal antibody against S. Recognizes S from Bovine coronavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

C Antibody, FITC conjugated

1-CSB-PA323345LC01RAI
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Description: A polyclonal antibody against C. Recognizes C from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

X Antibody, FITC conjugated

1-CSB-PA323774LC01WAW
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Description: A polyclonal antibody against X. Recognizes X from Woodchuck hepatitis B virus. This antibody is FITC conjugated. Tested in the following application: ELISA

P Antibody, FITC conjugated

1-CSB-PA324598LC01HDO
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Description: A polyclonal antibody against P. Recognizes P from Hepatitis B virus genotype A2 subtype adw2. This antibody is FITC conjugated. Tested in the following application: ELISA

NP Antibody, FITC conjugated

1-CSB-PA325769LC01IIM
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Description: A polyclonal antibody against NP. Recognizes NP from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

S Antibody, FITC conjugated

1-CSB-PA333052LC01BJO
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Description: A polyclonal antibody against S. Recognizes S from Bovine coronavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

E6 Antibody, FITC conjugated

1-CSB-PA334186LC01HNY
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Description: A polyclonal antibody against E6. Recognizes E6 from Human papillomavirus type 52. This antibody is FITC conjugated. Tested in the following application: ELISA

N Antibody, FITC conjugated

1-CSB-PA334828LC01PXE
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Description: A polyclonal antibody against N. Recognizes N from Puumala virus. This antibody is FITC conjugated. Tested in the following application: ELISA

S Antibody, FITC conjugated

1-CSB-PA336163EC01HIY
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Description: A polyclonal antibody against S. Recognizes S from Human coronavirus OC43. This antibody is FITC conjugated. Tested in the following application: ELISA

GP Antibody, FITC conjugated

1-CSB-PA350772LC01ZAT
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Description: A polyclonal antibody against GP. Recognizes GP from Zaire ebolavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

X Antibody, FITC conjugated

1-CSB-PA355969LC01HEM
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Description: A polyclonal antibody against X. Recognizes X from Hepatitis B virus genotype D subtype ayw. This antibody is FITC conjugated. Tested in the following application: ELISA

F Antibody, FITC conjugated

1-CSB-PA356041LC01HTO
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Description: A polyclonal antibody against F. Recognizes F from Human respiRatory syncytial virus A. This antibody is FITC conjugated. Tested in the following application: ELISA

NP Antibody, FITC conjugated

1-CSB-PA356056LC01IFZ
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Description: A polyclonal antibody against NP. Recognizes NP from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

NS Antibody, FITC conjugated

1-CSB-PA356065LC01IIE
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Description: A polyclonal antibody against NS. Recognizes NS from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

HA Antibody, FITC conjugated

1-CSB-PA356317LC01IDG
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Description: A polyclonal antibody against HA. Recognizes HA from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

NP Antibody, FITC conjugated

1-CSB-PA356318HC01IJU
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Description: A polyclonal antibody against NP. Recognizes NP from Influenza B virus. This antibody is FITC conjugated. Tested in the following application: ELISA

L2 Antibody, FITC conjugated

1-CSB-PA356939LC01HMN
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Description: A polyclonal antibody against L2. Recognizes L2 from Human papillomavirus type 18. This antibody is FITC conjugated. Tested in the following application: ELISA

GC Antibody, FITC conjugated

1-CSB-PA07569C0Rb
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Description: A polyclonal antibody against GC. Recognizes GC from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

MB Antibody, FITC conjugated

1-CSB-PA07917C0Rb
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Description: A polyclonal antibody against MB. Recognizes MB from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

L1 Antibody, FITC conjugated

1-CSB-PA08349C0Rb
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Description: A polyclonal antibody against L1. Recognizes L1 from Human papillomavirus type 16. This antibody is FITC conjugated. Tested in the following application: ELISA

L1 Antibody, FITC conjugated

1-CSB-PA08359C0Rb
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Description: A polyclonal antibody against L1. Recognizes L1 from Human papillomavirus type 18. This antibody is FITC conjugated. Tested in the following application: ELISA

C3 Antibody, FITC conjugated

1-CSB-PA10599C0Rb
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Description: A polyclonal antibody against C3. Recognizes C3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

C3 Antibody, FITC conjugated

1-CSB-PA360475HC01RA
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Description: A polyclonal antibody against C3. Recognizes C3 from Rat. This antibody is FITC conjugated. Tested in the following application: ELISA

NP Antibody, FITC conjugated

1-CSB-PA361330LC01IJK
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Description: A polyclonal antibody against NP. Recognizes NP from Influenza B virus. This antibody is FITC conjugated. Tested in the following application: ELISA

gG Antibody, FITC conjugated

1-CSB-PA361844HC01HWY
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Description: A polyclonal antibody against gG. Recognizes gG from Human herpesvirus 1. This antibody is FITC conjugated. Tested in the following application: ELISA

E7 Antibody, FITC conjugated

1-CSB-PA361948LC01HMN
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Description: A polyclonal antibody against E7. Recognizes E7 from Human papillomavirus type 18. This antibody is FITC conjugated. Tested in the following application: ELISA

E2 Antibody, FITC conjugated

1-CSB-PA361949LC01HMN
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Description: A polyclonal antibody against E2. Recognizes E2 from Human papillomavirus type 18. This antibody is FITC conjugated. Tested in the following application: ELISA

gB Antibody, FITC conjugated

1-CSB-PA362479LC01HJX
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Description: A polyclonal antibody against gB. Recognizes gB from Human herpesvirus 2. This antibody is FITC conjugated. Tested in the following application: ELISA

C3 Antibody, FITC conjugated

1-CSB-PA365507LC01MO
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Description: A polyclonal antibody against C3. Recognizes C3 from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

L2 Antibody, FITC conjugated

1-CSB-PA365848LC01HML
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Description: A polyclonal antibody against L2. Recognizes L2 from Human papillomavirus type 16. This antibody is FITC conjugated. Tested in the following application: ELISA

E6 Antibody, FITC conjugated

1-CSB-PA365854LC01HML
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Description: A polyclonal antibody against E6. Recognizes E6 from Human papillomavirus type 16. This antibody is FITC conjugated. Tested in the following application: ELISA

G Antibody, FITC conjugated

1-CSB-PA365937LC01HPO
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Description: A polyclonal antibody against G. Recognizes G from Human respiRatory syncytial virus A. This antibody is FITC conjugated. Tested in the following application: ELISA

2.5 Antibody, FITC conjugated

1-CSB-PA366021HC01EEB
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Description: A polyclonal antibody against 2.5. Recognizes 2.5 from Enterobacteria phage T7. This antibody is FITC conjugated. Tested in the following application: ELISA

G Antibody, FITC conjugated

1-CSB-PA389005LC01RIE
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Description: A polyclonal antibody against G. Recognizes G from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

PA Antibody, FITC conjugated

1-CSB-PA395880EC01ILR
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Description: A polyclonal antibody against PA. Recognizes PA from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

AK Antibody, FITC conjugated

1-CSB-PA511311HC01ETF
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Description: A polyclonal antibody against AK. Recognizes AK from Penaeus monodon. This antibody is FITC conjugated. Tested in the following application: ELISA

gL Antibody, FITC conjugated

1-CSB-PA515269LC01HWW
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Description: A polyclonal antibody against gL. Recognizes gL from Human cytomegalovirus. This antibody is FITC conjugated. Tested in the following application: ELISA

X Antibody, FITC conjugated

1-CSB-PA526046LC01HVP
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Description: A polyclonal antibody against X. Recognizes X from Hepatitis B virus genotype D. This antibody is FITC conjugated. Tested in the following application: ELISA

NP Antibody, FITC conjugated

1-CSB-PA529597LC01IMP
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Description: A polyclonal antibody against NP. Recognizes NP from Influenza A virus. This antibody is FITC conjugated. Tested in the following application: ELISA

TG Antibody, FITC conjugated

1-CSB-PA12325C0Rb
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  • 100ug
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Description: A polyclonal antibody against TG. Recognizes TG from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

KL Antibody, FITC conjugated

1-CSB-PA12729C0Rb
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  • 100ug
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Description: A polyclonal antibody against KL. Recognizes KL from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

CP Antibody, FITC conjugated

1-CSB-PA14599C0Rb
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  • 100ug
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Description: A polyclonal antibody against CP. Recognizes CP from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

HP Antibody, FITC conjugated

1-CSB-PA14609C0Rb
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  • 100ug
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Description: A polyclonal antibody against HP. Recognizes HP from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

G Antibody, FITC conjugated

1-CSB-PA14899C0Rb
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  • 100ug
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Description: A polyclonal antibody against G. Recognizes G from Rabies virus. This antibody is FITC conjugated. Tested in the following application: ELISA

Hp Antibody, FITC conjugated

1-CSB-PA17069C0Rb
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  • 100ug
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Description: A polyclonal antibody against Hp. Recognizes Hp from Rat. This antibody is FITC conjugated. Tested in the following application: ELISA

TF Antibody, FITC conjugated

1-CSB-PA00250G0Rb
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  • 100ug
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Description: A polyclonal antibody against TF. Recognizes TF from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

CD7 antibody - FITC conjugated

61R-2068 1000 tests
EUR 522
Description: Monoclonal CD7 FITC Conjugated Antibody

GK5 Antibody, FITC conjugated

1-CSB-PA744414LC01HU
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  • 100ug
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Description: A polyclonal antibody against GK5. Recognizes GK5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

EMB Antibody, FITC conjugated

1-CSB-PA754239LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against EMB. Recognizes EMB from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

IYD Antibody, FITC conjugated

1-CSB-PA754272LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against IYD. Recognizes IYD from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

SHF Antibody, FITC conjugated

1-CSB-PA755509LC01HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against SHF. Recognizes SHF from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

KLB Antibody, FITC conjugated

1-CSB-PA769815LC01HU
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  • 100ug
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Description: A polyclonal antibody against KLB. Recognizes KLB from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

PXK Antibody, FITC conjugated

1-CSB-PA770363LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against PXK. Recognizes PXK from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ssb Antibody, FITC conjugated

1-CSB-PA770616LC01BQE
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  • 100ug
  • 50ug
Description: A polyclonal antibody against ssb. Recognizes ssb from Bacillus anthracis. This antibody is FITC conjugated. Tested in the following application: ELISA

LTB Antibody, FITC conjugated

1-CSB-PA771253LC01EQV
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  • 100ug
  • 50ug
Description: A polyclonal antibody against LTB. Recognizes LTB from Chimpanzee. This antibody is FITC conjugated. Tested in the following application: ELISA

dye Antibody, FITC conjugated

1-CSB-PA772049LC01DIL
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  • 100ug
  • 50ug
Description: A polyclonal antibody against dye. Recognizes dye from Zebrafish. This antibody is FITC conjugated. Tested in the following application: ELISA

vcp Antibody, FITC conjugated

1-CSB-PA772050LC01DIL
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  • 100ul
  • 50ul
Description: A polyclonal antibody against vcp. Recognizes vcp from Zebrafish. This antibody is FITC conjugated. Tested in the following application: ELISA

RD3 Antibody, FITC conjugated

1-CSB-PA800101LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against RD3. Recognizes RD3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

LSR Antibody, FITC conjugated

1-CSB-PA801252LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against LSR. Recognizes LSR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

MKX Antibody, FITC conjugated

1-CSB-PA818257LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against MKX. Recognizes MKX from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AEN Antibody, FITC conjugated

1-CSB-PA819883LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AEN. Recognizes AEN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

RFK Antibody, FITC conjugated

1-CSB-PA836167LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against RFK. Recognizes RFK from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NPL Antibody, FITC conjugated

1-CSB-PA874830LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against NPL. Recognizes NPL from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

MRO Antibody, FITC conjugated

1-CSB-PA874842LC01HU
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  • 100ug
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Description: A polyclonal antibody against MRO. Recognizes MRO from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

SET Antibody, FITC conjugated

1-CSB-PA875345LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against SET. Recognizes SET from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AMN Antibody, FITC conjugated

1-CSB-PA880128LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AMN. Recognizes AMN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Gp2 Antibody, FITC conjugated

1-CSB-PA880511LC01MO
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  • 100ug
  • 50ug
Description: A polyclonal antibody against Gp2. Recognizes Gp2 from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

AK3 Antibody, FITC conjugated

1-CSB-PA883438LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AK3. Recognizes AK3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

FUZ Antibody, FITC conjugated

1-CSB-PA883593LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against FUZ. Recognizes FUZ from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

PG_1424 Antibody, FITC conjugated

1-CSB-PA886515LC01EYA
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  • 100ul
  • 50ul
Description: A polyclonal antibody against PG_1424. Recognizes PG_1424 from Porphyromonas gingivalis. This antibody is FITC conjugated. Tested in the following application: ELISA

Cbs Antibody, FITC conjugated

1-CSB-PA849665LC01MO
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  • 100ug
  • 50ug
Description: A polyclonal antibody against Cbs. Recognizes Cbs from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

SHD Antibody, FITC conjugated

1-CSB-PA850314LC01HU
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  • 100ug
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Description: A polyclonal antibody against SHD. Recognizes SHD from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ARX Antibody, FITC conjugated

1-CSB-PA850418LC01HU
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  • 100ug
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Description: A polyclonal antibody against ARX. Recognizes ARX from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

JMY Antibody, FITC conjugated

1-CSB-PA850838LC01HU
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  • 100ug
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Description: A polyclonal antibody against JMY. Recognizes JMY from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

MR1 Antibody, FITC conjugated

1-CSB-PA853268LC01HU
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  • 100ug
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Description: A polyclonal antibody against MR1. Recognizes MR1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

RPE Antibody, FITC conjugated

1-CSB-PA853385LC01HU
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  • 100ug
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Description: A polyclonal antibody against RPE. Recognizes RPE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

LPP Antibody, FITC conjugated

1-CSB-PA856611LC01HU
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  • 100ug
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Description: A polyclonal antibody against LPP. Recognizes LPP from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

SMO Antibody, FITC conjugated

1-CSB-PA857876LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against SMO. Recognizes SMO from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

FEV Antibody, FITC conjugated

1-CSB-PA858717LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against FEV. Recognizes FEV from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

scn Antibody, FITC conjugated

1-CSB-PA858805HC01SKY
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  • 100ug
  • 50ug
Description: A polyclonal antibody against scn. Recognizes scn from Staphylococcus aureus. This antibody is FITC conjugated. Tested in the following application: ELISA

NDN Antibody, FITC conjugated

1-CSB-PA859515LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against NDN. Recognizes NDN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

VP1 Antibody, FITC conjugated

1-CSB-PA859915LC01CID
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  • 100ul
  • 50ul
Description: A polyclonal antibody against VP1. Recognizes VP1 from Chicken anemia virus. This antibody is FITC conjugated. Tested in the following application: ELISA

MTR Antibody, FITC conjugated

1-CSB-PA859939LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against MTR. Recognizes MTR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

VP3 Antibody, FITC conjugated

1-CSB-PA860325DC01CID
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  • 100ug
  • 50ug
Description: A polyclonal antibody against VP3. Recognizes VP3 from Chicken anemia virus. This antibody is FITC conjugated. Tested in the following application: ELISA

WAC Antibody, FITC conjugated

1-CSB-PA861133HC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against WAC. Recognizes WAC from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DTL Antibody, FITC conjugated

1-CSB-PA889160LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against DTL. Recognizes DTL from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

TES Antibody, FITC conjugated

1-CSB-PA890679LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against TES. Recognizes TES from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DSE Antibody, FITC conjugated

1-CSB-PA890925LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against DSE. Recognizes DSE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ICK Antibody, FITC conjugated

1-CSB-PA891800LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against ICK. Recognizes ICK from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

BOK Antibody, FITC conjugated

1-CSB-PA892353LC01HU
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  • 100ug
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Description: A polyclonal antibody against BOK. Recognizes BOK from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

TNN Antibody, FITC conjugated

1-CSB-PA892498LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against TNN. Recognizes TNN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AK5 Antibody, FITC conjugated

1-CSB-PA897315LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AK5. Recognizes AK5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

UST Antibody, FITC conjugated

1-CSB-PA897525LC01HU
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  • 100ug
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Description: A polyclonal antibody against UST. Recognizes UST from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ACD Antibody, FITC conjugated

1-CSB-PA839289LC01HU
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  • 100ug
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Description: A polyclonal antibody against ACD. Recognizes ACD from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ADO Antibody, FITC conjugated

1-CSB-PA839416LC01HU
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  • 100ug
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Description: A polyclonal antibody against ADO. Recognizes ADO from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

These information had been corroborated by the growing of the basis imply sq. deviation worth (about 4.Four Å, calculated at 333 Okay) indicating that the presence of cationic headgroup at gold floor induce separation of the double strand. This discovering information paving the way in which for the event of nanostructured materials for photothermal-triggered supply methods of DNA for gene remedy software. Approval of nusinersen, an intrathecally administered antisense oligonucleotide, for the remedy of 5q-spinal muscular atrophy (SMA) marked the start of a brand new therapeutic period in neurological ailments.

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