[Rapid Screening System for Paralytic Shellfish Toxins in Bivalves by Oligonucleotide Lateral Flow Immunoassay]

[Rapid Screening System for Paralytic Shellfish Toxins in Bivalves by Oligonucleotide Lateral Flow Immunoassay]

The mouse bioassay (MBA) for paralytic shellfish toxins (PSTs) in bivalves has been used as an official methodology in Japan. It’s essential to develop another methodology to animal experiments in PSTs assay as a result of 3Rs (Substitute, Discount, and Refinement) of animal experiments are required from the animal welfare standpoint. Numerous strategies corresponding to HPLC-FL, receptor binding assay, LC-MS/MS and ELISA have been established to detect PSTs with out performing animal experiments.

The current examine was undertaken to develop a screening methodology utilizing oligonucleotide lateral move immunoassay (OLFIA) for detecting PSTs in bivalves. The screening stage was outlined as optimistic at 2 MU/g of MBA that’s the half regulation restrict of PSTs monitoring in Japan. All 20 optimistic (equal to or greater than 2 MU/g) samples judged from MBA confirmed a optimistic response within the OLFIA. No optimistic samples resulted in a false detrimental response. The OLFIA exhibited excessive accuracy at 2 MU/g of screening standards. The authors demonstrated right here that the OLFIA may be helpful for speedy detection of PSTs in bivalves.

Therapeutic oligonucleotides require the addition of a number of chemical modifications to the nucleosidic scaffold with a purpose to enhance their drug supply effectivity, cell penetration capability, organic stability, and pharmacokinetic properties. This chemical modification sample is commonly accompanied by an artificial burden and by limitations in sequence size. Right here, we now have synthesized a nucleoside triphosphate analog bearing two simultaneous modifications on the stage of the sugar (LNA) and the spine (thiophosphate) and have examined its compatibility with enzymatic DNA synthesis which may abrogate a few of these artificial limitations.

Whereas this novel analog shouldn’t be as nicely tolerated by polymerases in comparison with the corresponding α-thio-dTTP or LNA-TTP, α -thio-LNA-TTP can readily be used for enzymatic synthesis on common templates for the introduction of phosphorothioated LNA nucleotides.

Advances of Antisense Oligonucleotide Know-how within the Remedy of Hereditary Neurodegenerative Illnesses

Antisense nucleic acids are single-stranded oligonucleotides which were specifically chemically modified, which may bind to RNA expressed by goal genes by base complementary pairing and have an effect on protein synthesis on the stage of posttranscriptional processing or protein translation. Lately, the appliance of antisense nucleic acid expertise within the therapy of neuromuscular illnesses has made outstanding progress. In 2016, the US FDA permitted two antisense nucleic acid medicine for the therapy of Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA), and the event to deal with different neurodegenerative illnesses has additionally entered the medical stage.

Due to this fact, ASO represents a therapy with nice potential. The article will summarize ASO therapies when it comes to mechanism of motion, chemical modification, and administration strategies and analyze their function in a number of widespread neurodegenerative illnesses, corresponding to SMA, DMD, and amyotrophic lateral sclerosis (ALS).

This text systematically summarizes the nice potential of antisense nucleic acid expertise within the therapy of hereditary neurodegenerative illnesses. Dengue fever is among the commonest viral infections affecting people. It’s an increasing public well being drawback, significantly in tropical and subtropical areas. No efficient vaccine or antiviral therapies in opposition to Dengue virus (DENV) an infection can be found. Due to this fact, there’s a robust must develop secure and efficient therapeutic methods that may cut back the burden and length of hospitalizations as a consequence of this life-threatening illness.

[Rapid Screening System for Paralytic Shellfish Toxins in Bivalves by Oligonucleotide Lateral Flow Immunoassay]

A number of antisense oligonucleotides focused in opposition to monoacylglycerol acyltransferase 1 (Mogat1) enhance glucose metabolism independently of Mogat1

Monoacylglycerol acyltransferase (MGAT) enzymes catalyze the synthesis of diacylglycerol from monoacylglycerol. Earlier work has advised the significance of MGAT exercise within the growth of obesity-related hepatic insulin resistance. Certainly, antisense oligonucleotide (ASO)-mediated knockdown of Mogat1 mRNA, which encodes MGAT1, decreased hepatic MGAT exercise and improved glucose tolerance and insulin resistance in excessive fats eating regimen (HFD) fed mice. Nevertheless, current work has advised that some ASOs could have off-target results on physique weight and metabolic parameters through activation of the interferon alpha/beta receptor 1 (IFNAR-1) pathway.
Mice with whole-body Mogat1 knockout or a floxed allele for Mogat1 to permit for liver-specific Mogat1-knockout (by both a liver-specific transgenic or adeno-associated virus-driven Cre recombinase) had been generated. These mice had been positioned on a excessive fats eating regimen and glucose metabolism and insulin sensitivity was assessed after 16 weeks on eating regimen. In some experiments, mice had been handled with management scramble or Mogat1 ASOs within the presence or absence of IFNAR-1 neutralizing antibody.
Genetic deletion of hepatic Mogat1, both acutely or chronically, didn’t enhance hepatic steatosis, glucose tolerance, or insulin sensitivity in HFD-fed mice. Moreover, constitutive Mogat1 knockout in all tissues truly exacerbated HFD-induced weight problems, insulin sensitivity, and glucose intolerance on a HFD. Regardless of markedly decreased Mogat1 expression, liver MGAT exercise was unaffected in all knockout mouse fashions. Mogat1 overexpression in hepatocytes elevated liver MGAT exercise and TAG content material in low-fat fed mice, however didn’t trigger insulin resistance.

Niban (FAM129A) Antibody

abx020066-100ug 100 ug
EUR 526.8

Anti-FAM129A antibody

PAab02964 100 ug
EUR 426

Human Protein FAM129A (FAM129A) ELISA Kit

abx387256-96tests 96 tests
EUR 1093.2

FAM129A siRNA

20-abx901841
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

FAM129A siRNA

20-abx916028
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

FAM129A siRNA

20-abx916029
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti-FAM129A

LF-PA20345 100 ul
EUR 400.8
Description: Rabbit polyclonal to FAM129A

Phospho-FAM129A (Ser602) Antibody

CSB-PA589975-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-FAM129A (Ser602). Recognizes Phospho-FAM129A (Ser602) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-FAM129A (Ser602) Antibody

CSB-PA589975- each
EUR 402
Description: A polyclonal antibody against Phospho-FAM129A (Ser602). Recognizes Phospho-FAM129A (Ser602) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

FAM129A cloning plasmid

CSB-CL883649HU-10ug 10ug
EUR 1066.8
Description: A cloning plasmid for the FAM129A gene.

FAM129A Blocking Peptide

33R-8947 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FAM129A antibody, catalog no. 70R-1294

Anti-Phospho-FAM129A-(S602) antibody

STJ22138 100 µl
EUR 471.6
Description: This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated apoptosis.

Rat FAM129A shRNA Plasmid

20-abx986118
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse FAM129A shRNA Plasmid

20-abx975234
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human FAM129A shRNA Plasmid

20-abx964521
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

FAM129A ELISA KIT|Human

EF009516 96 Tests
EUR 826.8

Polyclonal FAM129A / NIBAN Antibody (aa908-920)

APR02341G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FAM129A / NIBAN (aa908-920). This antibody is tested and proven to work in the following applications:

Phospho-FAM129A-S602 Rabbit pAb

AP0350-100ul 100 ul
EUR 460.8

Phospho-FAM129A-S602 Rabbit pAb

AP0350-200ul 200 ul
EUR 664.8

Phospho-FAM129A-S602 Rabbit pAb

AP0350-20ul 20 ul Ask for price

Phospho-FAM129A-S602 Rabbit pAb

AP0350-50ul 50 ul
EUR 318

Fam129a ORF Vector (Rat) (pORF)

ORF066801 1.0 ug DNA
EUR 607.2

FAM129A ORF Vector (Human) (pORF)

ORF003782 1.0 ug DNA
EUR 114

Fam129a ORF Vector (Mouse) (pORF)

ORF044312 1.0 ug DNA
EUR 607.2

FAM129A sgRNA CRISPR Lentivector set (Human)

K0745601 3 x 1.0 ug
EUR 406.8

Human Protein Niban, FAM129A ELISA KIT

ELI-38137h 96 Tests
EUR 988.8

Mouse Protein Niban, Fam129a ELISA KIT

ELI-13123m 96 Tests
EUR 1038

Fam129a sgRNA CRISPR Lentivector set (Rat)

K7119001 3 x 1.0 ug
EUR 406.8

Fam129a sgRNA CRISPR Lentivector set (Mouse)

K4582201 3 x 1.0 ug
EUR 406.8

Rabbit Anti-Human FAM129A (aa 160-175) Polyclonal Antibody

CPB-1201RH 100 ul
EUR 552

Family With Sequence Similarity 129, Member A (FAM129A) Antibody

20-abx112435
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Family With Sequence Similarity 129, Member A (FAM129A) Antibody

abx232964-100ug 100 ug
EUR 577.2

Family with Sequence Similarity 129, Member A (FAM129A) Antibody

abx330391-100ul 100 ul
EUR 510

FAM129A sgRNA CRISPR Lentivector (Human) (Target 1)

K0745602 1.0 ug DNA
EUR 184.8

FAM129A sgRNA CRISPR Lentivector (Human) (Target 2)

K0745603 1.0 ug DNA
EUR 184.8

FAM129A sgRNA CRISPR Lentivector (Human) (Target 3)

K0745604 1.0 ug DNA
EUR 184.8

Fam129a sgRNA CRISPR Lentivector (Rat) (Target 1)

K7119002 1.0 ug DNA
EUR 184.8

Fam129a sgRNA CRISPR Lentivector (Rat) (Target 2)

K7119003 1.0 ug DNA
EUR 184.8

Fam129a sgRNA CRISPR Lentivector (Rat) (Target 3)

K7119004 1.0 ug DNA
EUR 184.8

Fam129a sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4582202 1.0 ug DNA
EUR 184.8

Fam129a sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4582203 1.0 ug DNA
EUR 184.8

Fam129a sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4582204 1.0 ug DNA
EUR 184.8

FAM129A Protein Vector (Human) (pPB-C-His)

PV015125 500 ng
EUR 394.8

FAM129A Protein Vector (Human) (pPB-N-His)

PV015126 500 ng
EUR 394.8

FAM129A Protein Vector (Human) (pPM-C-HA)

PV015127 500 ng
EUR 394.8

FAM129A Protein Vector (Human) (pPM-C-His)

PV015128 500 ng
EUR 394.8

FAM129A Protein Vector (Mouse) (pPB-C-His)

PV177246 500 ng
EUR 1278

FAM129A Protein Vector (Mouse) (pPB-N-His)

PV177247 500 ng
EUR 1278

FAM129A Protein Vector (Mouse) (pPM-C-HA)

PV177248 500 ng
EUR 1278

FAM129A Protein Vector (Mouse) (pPM-C-His)

PV177249 500 ng
EUR 1278

FAM129A Protein Vector (Rat) (pPB-C-His)

PV267202 500 ng
EUR 1399.2

FAM129A Protein Vector (Rat) (pPB-N-His)

PV267203 500 ng
EUR 1399.2

FAM129A Protein Vector (Rat) (pPM-C-HA)

PV267204 500 ng
EUR 1399.2

FAM129A Protein Vector (Rat) (pPM-C-His)

PV267205 500 ng
EUR 1399.2

FAM129A 3'UTR Luciferase Stable Cell Line

TU007554 1.0 ml
EUR 2799.6

Fam129a 3'UTR Luciferase Stable Cell Line

TU204267 1.0 ml Ask for price

Fam129a 3'UTR GFP Stable Cell Line

TU254267 1.0 ml Ask for price

Fam129a 3'UTR GFP Stable Cell Line

TU156139 1.0 ml Ask for price

Fam129a 3'UTR Luciferase Stable Cell Line

TU106139 1.0 ml Ask for price

FAM129A 3'UTR GFP Stable Cell Line

TU057554 1.0 ml
EUR 2799.6

FAM129A Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV626755 1.0 ug DNA
EUR 1626

FAM129A Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV626759 1.0 ug DNA
EUR 1626

FAM129A Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV626760 1.0 ug DNA
EUR 1626

Family with Sequence Similarity 129, Member A Phospho-Ser602 (FAM129A pS602) Antibody

abx332930-100ul 100 ul
EUR 560.4

FAM129A sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0745605 3 x 1.0 ug
EUR 451.2

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K7119005 3 x 1.0 ug
EUR 451.2

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4582205 3 x 1.0 ug
EUR 451.2

FAM129A sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0745606 1.0 ug DNA
EUR 200.4

FAM129A sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0745607 1.0 ug DNA
EUR 200.4

FAM129A sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0745608 1.0 ug DNA
EUR 200.4

FAM129A Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV626756 1.0 ug DNA
EUR 1626

FAM129A Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV626757 1.0 ug DNA
EUR 1695.6

FAM129A Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV626758 1.0 ug DNA
EUR 1695.6

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K7119006 1.0 ug DNA
EUR 200.4

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K7119007 1.0 ug DNA
EUR 200.4

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K7119008 1.0 ug DNA
EUR 200.4

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4582206 1.0 ug DNA
EUR 200.4

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4582207 1.0 ug DNA
EUR 200.4

Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4582208 1.0 ug DNA
EUR 200.4

ASAP1 antibody Antibody

DF8746 200ul
EUR 420

CD11b Antibody Antibody

ABD2911 100 ug
EUR 525.6

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 100 ug
EUR 525.6

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.08ML 0.08 ml
EUR 165

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.4ML 0.4 ml
EUR 379

Antibody

A1360-500 each Ask for price

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 627.6

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 343.2

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 469.2

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 577.2

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 661.2

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

CLCN5 Antibody / CIC-5 antibody

RQ6462 100ug
EUR 419
Description: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-100ul 100ul
EUR 399.6

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-50ul 50ul
EUR 286.8

Antibody Pair to ApoA-V antibody

10R-1876 100 ul
EUR 781.2
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-01mg 0,1 mg
EUR 321
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-1000ug 1000 ug
EUR 1539
Description: anti-CD22 monoclonal antibody

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103034
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103035
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103036
  • EUR 577.20
  • EUR 159.60
  • EUR 1696.80
  • EUR 794.40
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatitis C Virus Antibody (HCV) Antibody

abx023924-1mg 1 mg
EUR 1446

Anti-Glycoprotein 210 Antibody (gp210) Antibody

abx233571-100ug 100 ug
EUR 577.2

Anti Deoxyribonucleic Acid Antibody (DNA) Antibody

abx411057-50ug 50 ug
EUR 710.4

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319902
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319903
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319904
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319906
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319907
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319908
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319914
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319915
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319916
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319929
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319930
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319931
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (HRP)

20-abx311666
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (FITC)

20-abx311667
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (Biotin)

20-abx311668
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monoclonal NGF/proNGF Neutralizing Antibody Antibody

AMM06679G 0.05mg
EUR 633.6
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Goat anti- human Antibody^Polyclonal antibody

LSMab09896 100 ug
EUR 525.6

Antibody for Human alpha Tubulin Antibody

SPC-692D 0.1mg
EUR 424.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A390 0.1mg
EUR 481.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A488 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A565 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 565.
Apparently, a number of Mogat1 ASO sequences improved glucose tolerance in each wild-type and Mogat1 null mice, suggesting an off track impact. Hepatic IFNAR-1 signaling was activated by a number of Mogat1 ASOs however its blockade didn’t forestall the consequences of both Mogat1 ASO on glucose homeostasis. These outcomes point out that genetic lack of Mogat1 doesn’t have an effect on hepatic MGAT exercise or metabolic homeostasis on HFD and present that a number of Mogat1 ASOs enhance glucose metabolism by results impartial of focusing on Mogat1 or activation of IFNAR-1 signaling.

Leave a Reply

Your email address will not be published. Required fields are marked *