![[Rapid Screening System for Paralytic Shellfish Toxins in Bivalves by Oligonucleotide Lateral Flow Immunoassay]](https://www.iba-biotagnology.com/srh/uploads/2021/08/WhatsApp-Image-2021-07-18-at-10.44.30-AM.jpeg)
The mouse bioassay (MBA) for paralytic shellfish toxins (PSTs) in bivalves has been used as an official methodology in Japan. It’s essential to develop another methodology to animal experiments in PSTs assay as a result of 3Rs (Substitute, Discount, and Refinement) of animal experiments are required from the animal welfare standpoint. Numerous strategies corresponding to HPLC-FL, receptor binding assay, LC-MS/MS and ELISA have been established to detect PSTs with out performing animal experiments.
The current examine was undertaken to develop a screening methodology utilizing oligonucleotide lateral move immunoassay (OLFIA) for detecting PSTs in bivalves. The screening stage was outlined as optimistic at 2 MU/g of MBA that’s the half regulation restrict of PSTs monitoring in Japan. All 20 optimistic (equal to or greater than 2 MU/g) samples judged from MBA confirmed a optimistic response within the OLFIA. No optimistic samples resulted in a false detrimental response. The OLFIA exhibited excessive accuracy at 2 MU/g of screening standards. The authors demonstrated right here that the OLFIA may be helpful for speedy detection of PSTs in bivalves.
Therapeutic oligonucleotides require the addition of a number of chemical modifications to the nucleosidic scaffold with a purpose to enhance their drug supply effectivity, cell penetration capability, organic stability, and pharmacokinetic properties. This chemical modification sample is commonly accompanied by an artificial burden and by limitations in sequence size. Right here, we now have synthesized a nucleoside triphosphate analog bearing two simultaneous modifications on the stage of the sugar (LNA) and the spine (thiophosphate) and have examined its compatibility with enzymatic DNA synthesis which may abrogate a few of these artificial limitations.
Whereas this novel analog shouldn’t be as nicely tolerated by polymerases in comparison with the corresponding α-thio-dTTP or LNA-TTP, α -thio-LNA-TTP can readily be used for enzymatic synthesis on common templates for the introduction of phosphorothioated LNA nucleotides.
Advances of Antisense Oligonucleotide Know-how within the Remedy of Hereditary Neurodegenerative Illnesses
Antisense nucleic acids are single-stranded oligonucleotides which were specifically chemically modified, which may bind to RNA expressed by goal genes by base complementary pairing and have an effect on protein synthesis on the stage of posttranscriptional processing or protein translation. Lately, the appliance of antisense nucleic acid expertise within the therapy of neuromuscular illnesses has made outstanding progress. In 2016, the US FDA permitted two antisense nucleic acid medicine for the therapy of Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA), and the event to deal with different neurodegenerative illnesses has additionally entered the medical stage.
Due to this fact, ASO represents a therapy with nice potential. The article will summarize ASO therapies when it comes to mechanism of motion, chemical modification, and administration strategies and analyze their function in a number of widespread neurodegenerative illnesses, corresponding to SMA, DMD, and amyotrophic lateral sclerosis (ALS).
This text systematically summarizes the nice potential of antisense nucleic acid expertise within the therapy of hereditary neurodegenerative illnesses. Dengue fever is among the commonest viral infections affecting people. It’s an increasing public well being drawback, significantly in tropical and subtropical areas. No efficient vaccine or antiviral therapies in opposition to Dengue virus (DENV) an infection can be found. Due to this fact, there’s a robust must develop secure and efficient therapeutic methods that may cut back the burden and length of hospitalizations as a consequence of this life-threatening illness.
![[Rapid Screening System for Paralytic Shellfish Toxins in Bivalves by Oligonucleotide Lateral Flow Immunoassay]](https://www.iba-biotagnology.com/srh/uploads/2021/08/WhatsApp-Image-2021-07-18-at-10.44.30-AM-300x267.jpeg)
A number of antisense oligonucleotides focused in opposition to monoacylglycerol acyltransferase 1 (Mogat1) enhance glucose metabolism independently of Mogat1
Monoacylglycerol acyltransferase (MGAT) enzymes catalyze the synthesis of diacylglycerol from monoacylglycerol. Earlier work has advised the significance of MGAT exercise within the growth of obesity-related hepatic insulin resistance. Certainly, antisense oligonucleotide (ASO)-mediated knockdown of Mogat1 mRNA, which encodes MGAT1, decreased hepatic MGAT exercise and improved glucose tolerance and insulin resistance in excessive fats eating regimen (HFD) fed mice. Nevertheless, current work has advised that some ASOs could have off-target results on physique weight and metabolic parameters through activation of the interferon alpha/beta receptor 1 (IFNAR-1) pathway.
Mice with whole-body Mogat1 knockout or a floxed allele for Mogat1 to permit for liver-specific Mogat1-knockout (by both a liver-specific transgenic or adeno-associated virus-driven Cre recombinase) had been generated. These mice had been positioned on a excessive fats eating regimen and glucose metabolism and insulin sensitivity was assessed after 16 weeks on eating regimen. In some experiments, mice had been handled with management scramble or Mogat1 ASOs within the presence or absence of IFNAR-1 neutralizing antibody.
Genetic deletion of hepatic Mogat1, both acutely or chronically, didn’t enhance hepatic steatosis, glucose tolerance, or insulin sensitivity in HFD-fed mice. Moreover, constitutive Mogat1 knockout in all tissues truly exacerbated HFD-induced weight problems, insulin sensitivity, and glucose intolerance on a HFD. Regardless of markedly decreased Mogat1 expression, liver MGAT exercise was unaffected in all knockout mouse fashions. Mogat1 overexpression in hepatocytes elevated liver MGAT exercise and TAG content material in low-fat fed mice, however didn’t trigger insulin resistance.
Polyclonal FAM129A / NIBAN Antibody (aa908-920) |
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| APR02341G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FAM129A / NIBAN (aa908-920). This antibody is tested and proven to work in the following applications: |
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Fam129a/ Rat Fam129a ELISA Kit |
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| ELI-20717r | Lifescience Market | 96 Tests | EUR 1063.2 |
Human Protein FAM129A (FAM129A) ELISA Kit |
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| abx387256-96tests | Abbexa | 96 tests | EUR 1093.2 |
Rabbit Anti-Human FAM129A (aa 160-175) Polyclonal Antibody |
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| CPB-1201RH | Creative Diagnostics | 100 ul | EUR 552 |
Family With Sequence Similarity 129, Member A (FAM129A) Antibody |
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| abx232964-100ug | Abbexa | 100 ug | EUR 577.2 |
Family with Sequence Similarity 129, Member A (FAM129A) Antibody |
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| abx330391-100ul | Abbexa | 100 ul | EUR 510 |
Family With Sequence Similarity 129, Member A (FAM129A) Antibody |
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| 20-abx112435 | Abbexa |
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FAM129A siRNA |
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| 20-abx916028 | Abbexa |
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FAM129A siRNA |
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| 20-abx916029 | Abbexa |
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FAM129A siRNA |
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| 20-abx901841 | Abbexa |
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FAM129A cloning plasmid |
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| CSB-CL883649HU-10ug | Cusabio | 10ug | EUR 1066.8 |
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Description: A cloning plasmid for the FAM129A gene. |
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FAM129A Blocking Peptide |
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| 33R-8947 | Fitzgerald | 100 ug | EUR 216 |
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Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FAM129A antibody, catalog no. 70R-1294 |
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FAM129A ELISA KIT|Human |
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| EF009516 | Lifescience Market | 96 Tests | EUR 826.8 |
Rat FAM129A shRNA Plasmid |
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| 20-abx986118 | Abbexa |
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Mouse FAM129A shRNA Plasmid |
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| 20-abx975234 | Abbexa |
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Human FAM129A shRNA Plasmid |
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| 20-abx964521 | Abbexa |
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Family with Sequence Similarity 129, Member A Phospho-Ser602 (FAM129A pS602) Antibody |
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| abx332930-100ul | Abbexa | 100 ul | EUR 560.4 |
Fam129a ORF Vector (Rat) (pORF) |
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| ORF066801 | ABM | 1.0 ug DNA | EUR 607.2 |
FAM129A ORF Vector (Human) (pORF) |
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| ORF003782 | ABM | 1.0 ug DNA | EUR 114 |
Fam129a ORF Vector (Mouse) (pORF) |
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| ORF044312 | ABM | 1.0 ug DNA | EUR 607.2 |
Human Protein Niban, FAM129A ELISA KIT |
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| ELI-38137h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse Protein Niban, Fam129a ELISA KIT |
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| ELI-13123m | Lifescience Market | 96 Tests | EUR 1038 |
Fam129a sgRNA CRISPR Lentivector set (Rat) |
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| K7119001 | ABM | 3 x 1.0 ug | EUR 406.8 |
Fam129a sgRNA CRISPR Lentivector set (Mouse) |
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| K4582201 | ABM | 3 x 1.0 ug | EUR 406.8 |
FAM129A sgRNA CRISPR Lentivector set (Human) |
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| K0745601 | ABM | 3 x 1.0 ug | EUR 406.8 |
Fam129a 3'UTR GFP Stable Cell Line |
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| TU156139 | ABM | 1.0 ml | Ask for price |
FAM129A 3'UTR GFP Stable Cell Line |
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| TU057554 | ABM | 1.0 ml | EUR 2799.6 |
Fam129a 3'UTR GFP Stable Cell Line |
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| TU254267 | ABM | 1.0 ml | Ask for price |
FAM129A Protein Vector (Rat) (pPM-C-HA) |
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| PV267204 | ABM | 500 ng | EUR 1399.2 |
FAM129A Protein Vector (Rat) (pPB-C-His) |
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| PV267202 | ABM | 500 ng | EUR 1399.2 |
FAM129A Protein Vector (Rat) (pPB-N-His) |
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| PV267203 | ABM | 500 ng | EUR 1399.2 |
FAM129A Protein Vector (Rat) (pPM-C-His) |
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| PV267205 | ABM | 500 ng | EUR 1399.2 |
FAM129A Protein Vector (Human) (pPM-C-HA) |
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| PV015127 | ABM | 500 ng | EUR 394.8 |
FAM129A Protein Vector (Mouse) (pPM-C-HA) |
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| PV177248 | ABM | 500 ng | EUR 1278 |
FAM129A Protein Vector (Human) (pPB-C-His) |
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| PV015125 | ABM | 500 ng | EUR 394.8 |
FAM129A Protein Vector (Human) (pPB-N-His) |
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| PV015126 | ABM | 500 ng | EUR 394.8 |
FAM129A Protein Vector (Human) (pPM-C-His) |
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| PV015128 | ABM | 500 ng | EUR 394.8 |
FAM129A Protein Vector (Mouse) (pPB-C-His) |
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| PV177246 | ABM | 500 ng | EUR 1278 |
FAM129A Protein Vector (Mouse) (pPB-N-His) |
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| PV177247 | ABM | 500 ng | EUR 1278 |
FAM129A Protein Vector (Mouse) (pPM-C-His) |
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| PV177249 | ABM | 500 ng | EUR 1278 |
FAM129A 3'UTR Luciferase Stable Cell Line |
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| TU007554 | ABM | 1.0 ml | EUR 2799.6 |
Fam129a 3'UTR Luciferase Stable Cell Line |
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| TU106139 | ABM | 1.0 ml | Ask for price |
Fam129a 3'UTR Luciferase Stable Cell Line |
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| TU204267 | ABM | 1.0 ml | Ask for price |
Fam129a sgRNA CRISPR Lentivector (Rat) (Target 1) |
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| K7119002 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129a sgRNA CRISPR Lentivector (Rat) (Target 2) |
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| K7119003 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129a sgRNA CRISPR Lentivector (Rat) (Target 3) |
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| K7119004 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129a sgRNA CRISPR Lentivector (Mouse) (Target 1) |
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| K4582202 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129a sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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| K4582203 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129a sgRNA CRISPR Lentivector (Mouse) (Target 3) |
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| K4582204 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129A sgRNA CRISPR Lentivector (Human) (Target 1) |
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| K0745602 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129A sgRNA CRISPR Lentivector (Human) (Target 2) |
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| K0745603 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129A sgRNA CRISPR Lentivector (Human) (Target 3) |
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| K0745604 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129A Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
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| LV626755 | ABM | 1.0 ug DNA | EUR 1626 |
FAM129A Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC) |
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| LV626759 | ABM | 1.0 ug DNA | EUR 1626 |
FAM129A Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a) |
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| LV626760 | ABM | 1.0 ug DNA | EUR 1626 |
FAM171A2 Antibody |
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| 47788-100ul | SAB | 100ul | EUR 302.4 |
FAM114A2 Antibody |
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| DF14482 | Affbiotech | 100ul | EUR 420 |
FAM160A2 Antibody |
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| 1-CSB-PA822711LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM160A2. Recognizes FAM160A2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM114A2 Antibody |
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| 1-CSB-PA878875LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM114A2. Recognizes FAM114A2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
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FAM126A antibody |
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| 23161-100ul | SAB | 100ul | EUR 468 |
FAM120A Antibody |
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| 24950-100ul | SAB | 100ul | EUR 468 |
FAM234A Antibody |
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| 43873-100ul | SAB | 100ul | EUR 302.4 |
FAM101A Antibody |
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| 43371-100ul | SAB | 100ul | EUR 302.4 |
FAM120A antibody |
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| 70R-2701 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM120A antibody raised against the middle region of FAM120A |
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Fam168a antibody |
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| 70R-9312 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal Fam168a antibody |
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FAM126A antibody |
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| 70R-10016 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal FAM126A antibody |
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FAM161A antibody |
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| 70R-10072 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal FAM161A antibody |
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FAM161A antibody |
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| 70R-10073 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal FAM161A antibody |
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FAM107A antibody |
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| 70R-1070 | Fitzgerald | 100 ug | EUR 452.4 |
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Description: Rabbit polyclonal FAM107A antibody raised against the middle region of FAM107A |
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FAM120A Antibody |
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| 5307-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: FAM120A Antibody: FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells. |
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FAM120A Antibody |
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| 5307-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: FAM120A Antibody: FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells. |
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FAM212A Antibody |
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| 5531-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1). FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1). In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2). |
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FAM212A Antibody |
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| 5531-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1). FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1). In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2). |
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FAM101A antibody |
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| 70R-17202 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM101A antibody |
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FAM107A antibody |
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| 70R-17203 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM107A antibody |
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FAM119A antibody |
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| 70R-17207 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM119A antibody |
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FAM120A antibody |
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| 70R-17208 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM120A antibody |
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FAM127A antibody |
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| 70R-17210 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM127A antibody |
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FAM156A antibody |
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| 70R-17213 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM156A antibody |
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FAM175A antibody |
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| 70R-17215 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM175A antibody |
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FAM185A antibody |
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| 70R-17216 | Fitzgerald | 50 ul | EUR 522 |
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Description: Rabbit polyclonal FAM185A antibody |
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FAM126A antibody |
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| 70R-13360 | Fitzgerald | 100 ul | EUR 548.4 |
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Description: Affinity purified Rabbit polyclonal FAM126A antibody |
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FAM105A antibody |
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| 70R-6746 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM105A antibody raised against the N terminal of FAM105A |
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FAM105A antibody |
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| 70R-6892 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM105A antibody raised against the middle region of FAM105A |
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FAM134A antibody |
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| 70R-6908 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM134A antibody raised against the N terminal of FAM134A |
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FAM119A antibody |
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| 70R-3148 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM119A antibody raised against the middle region of FAM119A |
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FAM119A antibody |
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| 70R-3617 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM119A antibody raised against the N terminal of FAM119A |
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FAM124A antibody |
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| 70R-3890 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM124A antibody raised against the middle region of FAM124A |
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FAM109A antibody |
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| 70R-4010 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM109A antibody raised against the N terminal of FAM109A |
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FAM113A antibody |
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| 70R-4106 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM113A antibody raised against the N terminal of FAM113A |
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FAM113A antibody |
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| 70R-4107 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM113A antibody raised against the C terminal of FAM113A |
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FAM116A antibody |
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| 70R-4205 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM116A antibody raised against the middle region of FAM116A |
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FAM118A antibody |
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| 70R-4554 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM118A antibody raised against the middle region of FAM118A |
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FAM156A antibody |
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| 70R-4820 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM156A antibody raised against the middle region of FAM156A |
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FAM156A antibody |
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| 70R-4887 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM156A antibody raised against the N terminal of FAM156A |
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FAM101A antibody |
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| 70R-3401 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Rabbit polyclonal FAM101A antibody raised against the middle region of FAM101A |
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FAM107A Antibody |
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| 36461-100ul | SAB | 100ul | EUR 302.4 |
FAM175A Antibody |
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| 46563-100ul | SAB | 100ul | EUR 302.4 |
FAM105A Antibody |
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| 47118-100ul | SAB | 100ul | EUR 302.4 |
FAM198A Antibody |
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| 47119-100ul | SAB | 100ul | EUR 302.4 |
FAM213A Antibody |
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| 47532-100ul | SAB | 100ul | EUR 302.4 |
FAM200A Antibody |
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| 47542-100ul | SAB | 100ul | EUR 302.4 |
FAM167A Antibody |
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| DF16060 | Affbiotech | 100ul | EUR 420 |
FAM181A Antibody |
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| DF15082 | Affbiotech | 100ul | EUR 420 |
FAM172A Antibody |
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| DF15097 | Affbiotech | 100ul | EUR 420 |
FAM135A Antibody |
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| DF15159 | Affbiotech | 100ul | EUR 420 |
FAM184A Antibody |
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| DF15162 | Affbiotech | 100ul | EUR 420 |
FAM162A Antibody |
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| DF15168 | Affbiotech | 100ul | EUR 420 |
FAM111A Antibody |
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| DF15461 | Affbiotech | 100ul | EUR 420 |
FAM107A Antibody |
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| 1-CSB-PA118886 | Cusabio |
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Description: A polyclonal antibody against FAM107A. Recognizes FAM107A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
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FAM136A Antibody |
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| 1-CSB-PA836190LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM136A. Recognizes FAM136A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
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FAM167A Antibody |
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| 1-CSB-PA836244LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM167A. Recognizes FAM167A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM105A Antibody |
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| 1-CSB-PA873659LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM105A. Recognizes FAM105A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
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FAM156A Antibody |
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| 1-CSB-PA847690LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM156A. Recognizes FAM156A from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
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FAM174A Antibody |
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| 1-CSB-PA851535LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM174A. Recognizes FAM174A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM163A Antibody |
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| 1-CSB-PA853423LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM163A. Recognizes FAM163A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM111A Antibody |
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| 1-CSB-PA853484LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM111A. Recognizes FAM111A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
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FAM118A Antibody |
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| 1-CSB-PA885747LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM118A. Recognizes FAM118A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
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FAM234A Antibody |
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| 1-CSB-PA887949LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM234A. Recognizes FAM234A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200 |
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FAM124A Antibody |
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| 1-CSB-PA801237LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM124A. Recognizes FAM124A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM156A Antibody |
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| 1-CSB-PA008097GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM156A. Recognizes FAM156A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC |
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FAM175A Antibody |
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| 1-CSB-PA008138GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM175A. Recognizes FAM175A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
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FAM185A Antibody |
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| 1-CSB-PA008159GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM185A. Recognizes FAM185A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
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FAM101A Antibody |
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| 1-CSB-PA007975GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM101A. Recognizes FAM101A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
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FAM107A Antibody |
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| 1-CSB-PA007987GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM107A. Recognizes FAM107A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF |
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FAM107A Antibody |
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| 1-CSB-PA007987LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM107A. Recognizes FAM107A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM120A Antibody |
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| 1-CSB-PA008027GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM120A. Recognizes FAM120A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
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FAM127A Antibody |
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| 1-CSB-PA008044GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM127A. Recognizes FAM127A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC |
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FAM127A Antibody |
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| 1-CSB-PA008044LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM127A. Recognizes FAM127A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
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FAM161A Antibody |
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| 1-CSB-PA661553LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM161A. Recognizes FAM161A from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
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FAM182A Antibody |
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| 1-CSB-PA729200LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM182A. Recognizes FAM182A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200 |
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FAM131A Antibody |
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| 1-CSB-PA744268LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM131A. Recognizes FAM131A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM166A Antibody |
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| 1-CSB-PA753727LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM166A. Recognizes FAM166A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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FAM107A Antibody |
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| 1-CSB-PA775661 | Cusabio |
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Description: A polyclonal antibody against FAM107A. Recognizes FAM107A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
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FAM195A Antibody |
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| 1-CSB-PA003276GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM195A. Recognizes FAM195A from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF |
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Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
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| K7119005 | ABM | 3 x 1.0 ug | EUR 451.2 |
Fam129a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
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| K4582205 | ABM | 3 x 1.0 ug | EUR 451.2 |
FAM129A sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
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| K0745605 | ABM | 3 x 1.0 ug | EUR 451.2 |
anti- FAM114A1 antibody |
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| FNab02955 | FN Test | 100µg | EUR 606.3 |
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Description: Antibody raised against FAM114A1 |
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FAM43A Antibody |
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| 20-abx318118 | Abbexa |
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FAM69A Antibody |
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| 20-abx318582 | Abbexa |
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FAM63A Antibody |
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| 20-abx318639 | Abbexa |
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FAM62A Antibody |
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| abx232990-100ug | Abbexa | 100 ug | EUR 610.8 |
FAM96A Antibody |
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| abx145971-100ug | Abbexa | 100 ug | EUR 469.2 |
FAM96A Antibody |
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| abx146049-100ug | Abbexa | 100 ug | EUR 469.2 |
FAM96A Antibody |
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| abx146066-100ug | Abbexa | 100 ug | EUR 469.2 |
FAM63A Antibody |
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| abx146098-100ug | Abbexa | 100 ug | EUR 469.2 |
FAM40A antibody |
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| 10R-4057 | Fitzgerald | 100 ul | EUR 871.2 |
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Description: Mouse monoclonal FAM40A antibody |
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FAM40A antibody |
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| 10R-4058 | Fitzgerald | 100 ul | EUR 829.2 |
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Description: Mouse monoclonal FAM40A antibody |
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FAM59A Antibody |
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| 25001-100ul | SAB | 100ul | EUR 468 |
FAM50A antibody |
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| 22337-100ul | SAB | 100ul | EUR 468 |
FAM96A Antibody |
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| 43380-100ul | SAB | 100ul | EUR 302.4 |
FAM53A antibody |
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| 70R-9126 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal FAM53A antibody |
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FAM71A antibody |
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| 70R-9219 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal FAM71A antibody |
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FAM78A antibody |
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| 70R-9322 | Fitzgerald | 50 ug | EUR 560.4 |
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Description: Affinity purified rabbit polyclonal FAM78A antibody |
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Apparently, a number of Mogat1 ASO sequences improved glucose tolerance in each wild-type and Mogat1 null mice, suggesting an off track impact. Hepatic IFNAR-1 signaling was activated by a number of Mogat1 ASOs however its blockade didn’t forestall the consequences of both Mogat1 ASO on glucose homeostasis. These outcomes point out that genetic lack of Mogat1 doesn’t have an effect on hepatic MGAT exercise or metabolic homeostasis on HFD and present that a number of Mogat1 ASOs enhance glucose metabolism by results impartial of focusing on Mogat1 or activation of IFNAR-1 signaling.