Single Copy Oligonucleotide Fluorescence In Situ Hybridization Probe Design Platforms: Development, Application and Evaluation

Single Copy Oligonucleotide Fluorescence In Situ Hybridization Probe Design Platforms: Development, Application and Evaluation

Oligonucleotides fluorescence in situ hybridization (Oligo-FISH) is an rising know-how and is a crucial device in analysis areas comparable to detection of chromosome variation, identification of allopolyploid, and deciphering of three-dimensional (3D) genome constructions. Primarily based on the demand for extremely environment friendly oligo probes for oligo-FISH experiments, growing numbers of instruments have been developed for probe design lately. Out of date oligonucleotide design instruments have been tailored for oligo-FISH probe design due to their comparable issues.

With the event of DNA sequencing and large-scale synthesis, novel instruments have been designed to extend the specificity of designed oligo probes and allow genome-scale oligo probe design, which has tremendously improved the appliance of single copy oligo-FISH. Regardless of this, few research have launched the event of the oligo-FISH probe design instruments and their utility in FISH experiments systematically. Apart from, a complete comparability and analysis is missing for the out there instruments. On this evaluation, we offer an outline of the oligo-FISH probe design course of, summarize the event and utility of the out there instruments, consider a number of state-of-art instruments, and finally present steering for single copy oligo-FISH probe design.

At the moment there’s an pressing must develop antiviral medicine and alleviate present COVID-19 pandemic. Though many candidates have been developed, we right here designed and constructed chimeric oligonucleotides comprising a 2′-OMe modified antisense oligonucleotide and a 5′-phosphorylated 2′-5′ poly(A) 4 (4A 2-5 ) to degrade envelope and spike RNAs of SARS-CoV-2. The oligonucleotide was used for looking and recognizing goal viral RNA sequence, and the conjugated 4A 2-5 was used for guided ribonuclease L (RNase L) activation to sequence-specifically degrade viral RNAs.

Since RNase L can potently cleave single strand RNA throughout innate antiviral response, degradation efficiencies with these chimeras have been twice as a lot as solely 2′-OMe modified oligonucleotides for each SARS-CoV-2 RNA targets. In pseudovirus an infection fashions, one of many chimeras concentrating on spike RNA achieved potent and broad-spectrum inhibition of SARS-CoV-2 and its N501Y and/or ΔH69/ΔV70 mutants.

Simultaneous quantitation of inorganic ions in oligonucleotides utilizing mixed-mode liquid chromatography coupled with a charged aerosol detector

The quantities of inorganic ions (e.g. sodium, potassium, magnesium, calcium, chloride, and phosphate) in intrathecally administered oligonucleotide drug merchandise should be managed with a view to meet the ultimate goal formulation composition. Throughout course of growth, these ions are measured to make sure the answer composition doesn’t change throughout purification or drug product compounding and to make sure the ultimate drug product targets are achieved.

A quantitative methodology for ion evaluation in antisense oligonucleotide (ASO) medicine was developed by mixed-mode anion trade/cation exchange-hydrophilic interplay liquid chromatography (AEX/CEX-HILIC) with a charged aerosol detector (CAD). This thirteen-minute methodology measures monovalent and multivalent cations and anions concurrently. LC separation circumstances, CAD parameters, and pattern preparation have been judiciously optimized to make sure that the strategy is restricted, correct, exact, linear, strong, and rugged. With this LC-CAD method, ion evaluation for oligonucleotide medicine may be carried out in most analytical labs to help drug growth.

Single Copy Oligonucleotide Fluorescence In Situ Hybridization Probe Design Platforms: Development, Application and Evaluation

Antisense Oligonucleotide-Mediated Discount of HDAC6 Does Not Scale back Tau Pathology in P301S Tau Transgenic Mice

Acetylation of tau protein is dysregulated in Alzheimer’s Illness (AD). It has been proposed that acetylation of particular websites within the KXGS motif of tau can regulate phosphorylation of close by residues and scale back the propensity of tau to mixture. Histone deacetylase 6 (HDAC6) is a cytoplasmic enzyme concerned in deacetylation of a number of targets, together with tau, and it has been steered that inhibition of HDAC6 would enhance tau acetylation on the KXGS motifs and thus might current a viable therapeutic method to deal with AD.

To instantly take a look at the contribution of HDAC6 to tau pathology, we intracerebroventricularly injected an antisense oligonucleotide (ASO) directed towards HDAC6 mRNA into brains of P301S tau mice (PS19 mannequin), which resulted in a 70% knockdown of HDAC6 protein within the mind. Regardless of a sturdy lower in ranges of HDAC6, no enhance in tau acetylation was noticed. Moreover, no change of tau phosphorylation or tau aggregation was detected upon the knockdown of HDAC6. We conclude that HDAC6 doesn’t affect tau pathology in PS19 mice.

Efficient silencing of miR-126 after ischemic stroke via intravenous α-tocopherol-conjugated heteroduplex oligonucleotide in mice

Mind endothelial cells (BECs) are concerned within the pathogenesis of ischemic stroke. Lately, a number of microRNAs (miRNAs) in BECs have been reported to manage the endothelial operate in ischemic mind. Due to this fact, modulation of miRNAs in BECs by a therapeutic oligonucleotide to inhibit miRNA (antimiR) might be a helpful technique for treating ischemic stroke. Nevertheless, few makes an attempt have been made to realize this technique through systemic route because of lack of environment friendly delivery-method towards BECs.

Right here, we have now developed a brand new know-how for delivering an antimiR into BECs and silencing miRNAs in BECs, utilizing a mouse ischemic stroke mannequin. We designed a heteroduplex oligonucleotide, comprising an antimiR towards miRNA-126 (miR-126) often called the endothelial-specific miRNA and its complementary RNA, conjugated to α-tocopherol as a supply ligand (Toc-HDO concentrating on miR-126). Intravenous administration of Toc-HDO concentrating on miR-126 remarkably suppressed miR-126 expression in ischemic mind of the mannequin mice.

Human Protein FAM129B (FAM129B) ELISA Kit

abx387257-96tests 96 tests
EUR 1093.2

FAM129B siRNA

20-abx901842
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

FAM129B siRNA

20-abx916030
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

FAM129B siRNA

20-abx916031
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

FAM129B (Ab-712) Antibody

CSB-PA998601-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against FAM129B (Ab-712). Recognizes FAM129B (Ab-712) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

FAM129B (Ab-712) Antibody

CSB-PA998601- each
EUR 402
Description: A polyclonal antibody against FAM129B (Ab-712). Recognizes FAM129B (Ab-712) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

FAM129B Antibody / MINERVA / NIBAN2

RQ6569 100ug
EUR 419
Description: FAM129B/Niban-like protein 1 (family with sequence similarity 129, member B) belongs to a poorly characterized family of Niban proteins that also includes FAM129A/Niban and FAM129C/Niban-like protein 2. FAM129A/Niban is implicated in the ER stress response and is upregulated at the protein level in thyroid carcinoma. FAM129C/Niban-like protein 2 is preferentially expressed in B-cells and is one of five biomarkers upregulated in whole blood from patients with colorectal carcinoma. FAM129B is broadly expressed and has been shown to be a downstream target of B-Raf in melanoma cells. Though FAM129B does not appear to regulate cell growth and division, phosphorylation of FAM129B by B-Raf is essential for the invasive potential of melanoma and non-melanoma cell lines. Deletion of FAM129B in melanoma cells significantly impairs B-Raf/MEK/Erk-dependent invasion into the extracellular matrix.

pCMV-SPORT6-FAM129B

PVT12950 2 ug
EUR 469.2

Rabbit Anti-Human FAM129B (aa 710-714) Polyclonal Antibody

CPB-1199RH 100 ul
EUR 552

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

Human FAM129B shRNA Plasmid

20-abx962121
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse FAM129B shRNA Plasmid

20-abx981593
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Rat FAM129B shRNA Plasmid

20-abx990325
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

FAM129B ELISA KIT|Human

EF009517 96 Tests
EUR 826.8

FAM129B Recombinant Protein (Rat)

RP200402 100 ug Ask for price

FAM129B Recombinant Protein (Human)

RP057474 100 ug Ask for price

FAM129B Recombinant Protein (Mouse)

RP132935 100 ug Ask for price

Fam129b ORF Vector (Rat) (pORF)

ORF066802 1.0 ug DNA
EUR 607.2

FAM129B ORF Vector (Human) (pORF)

ORF019159 1.0 ug DNA
EUR 486

Fam129b ORF Vector (Mouse) (pORF)

ORF044313 1.0 ug DNA
EUR 607.2

FAM129B sgRNA CRISPR Lentivector set (Human)

K0745701 3 x 1.0 ug
EUR 406.8

Fam129b sgRNA CRISPR Lentivector set (Mouse)

K4870701 3 x 1.0 ug
EUR 406.8

Fam129b sgRNA CRISPR Lentivector set (Rat)

K6504001 3 x 1.0 ug
EUR 406.8

Family with Sequence Similarity 129, Member B (FAM129B) Antibody

abx331409-100ul 100 ul
EUR 510

Family With Sequence Similarity 129, Member B (FAM129B) Antibody

abx232965-100ug 100 ug
EUR 610.8

FAM129B sgRNA CRISPR Lentivector (Human) (Target 1)

K0745702 1.0 ug DNA
EUR 184.8

FAM129B sgRNA CRISPR Lentivector (Human) (Target 2)

K0745703 1.0 ug DNA
EUR 184.8

FAM129B sgRNA CRISPR Lentivector (Human) (Target 3)

K0745704 1.0 ug DNA
EUR 184.8

Fam129b sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4870702 1.0 ug DNA
EUR 184.8

Fam129b sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4870703 1.0 ug DNA
EUR 184.8

Fam129b sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4870704 1.0 ug DNA
EUR 184.8

Fam129b sgRNA CRISPR Lentivector (Rat) (Target 1)

K6504002 1.0 ug DNA
EUR 184.8

Fam129b sgRNA CRISPR Lentivector (Rat) (Target 2)

K6504003 1.0 ug DNA
EUR 184.8

Fam129b sgRNA CRISPR Lentivector (Rat) (Target 3)

K6504004 1.0 ug DNA
EUR 184.8

FAM129B Protein Vector (Human) (pPB-C-His)

PV076633 500 ng
EUR 662.4

FAM129B Protein Vector (Human) (pPB-N-His)

PV076634 500 ng
EUR 662.4

FAM129B Protein Vector (Human) (pPM-C-HA)

PV076635 500 ng
EUR 662.4

FAM129B Protein Vector (Human) (pPM-C-His)

PV076636 500 ng
EUR 662.4

FAM129B Protein Vector (Mouse) (pPB-C-His)

PV177250 500 ng
EUR 1278

FAM129B Protein Vector (Mouse) (pPB-N-His)

PV177251 500 ng
EUR 1278

FAM129B Protein Vector (Mouse) (pPM-C-HA)

PV177252 500 ng
EUR 1278

FAM129B Protein Vector (Mouse) (pPM-C-His)

PV177253 500 ng
EUR 1278

FAM129B 3'UTR Luciferase Stable Cell Line

TU007555 1.0 ml
EUR 1825.2

Fam129b 3'UTR GFP Stable Cell Line

TU254268 1.0 ml Ask for price

Fam129b 3'UTR Luciferase Stable Cell Line

TU106140 1.0 ml Ask for price

FAM129B 3'UTR GFP Stable Cell Line

TU057555 1.0 ml
EUR 1825.2

Fam129b 3'UTR Luciferase Stable Cell Line

TU204268 1.0 ml Ask for price

Fam129b 3'UTR GFP Stable Cell Line

TU156140 1.0 ml Ask for price

FAM129B Protein Vector (Rat) (pPB-C-His)

PV267206 500 ng
EUR 1399.2

FAM129B Protein Vector (Rat) (pPB-N-His)

PV267207 500 ng
EUR 1399.2

FAM129B Protein Vector (Rat) (pPM-C-HA)

PV267208 500 ng
EUR 1399.2

FAM129B Protein Vector (Rat) (pPM-C-His)

PV267209 500 ng
EUR 1399.2

Mouse Niban- like protein 1, Fam129b ELISA KIT

ELI-35343m 96 Tests
EUR 1038

FAM129B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV667033 1.0 ug DNA
EUR 1626

FAM129B Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV667037 1.0 ug DNA
EUR 1626

FAM129B Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV667038 1.0 ug DNA
EUR 1626

Human Niban- like protein 1, FAM129B ELISA KIT

ELI-13124h 96 Tests
EUR 988.8

FAM129B sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0745705 3 x 1.0 ug
EUR 451.2

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4870705 3 x 1.0 ug
EUR 451.2

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6504005 3 x 1.0 ug
EUR 451.2

FAM129B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV667034 1.0 ug DNA
EUR 1626

FAM129B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV667035 1.0 ug DNA
EUR 1695.6

FAM129B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV667036 1.0 ug DNA
EUR 1695.6

FAM129B sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0745706 1.0 ug DNA
EUR 200.4

FAM129B sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0745707 1.0 ug DNA
EUR 200.4

FAM129B sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0745708 1.0 ug DNA
EUR 200.4

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4870706 1.0 ug DNA
EUR 200.4

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4870707 1.0 ug DNA
EUR 200.4

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4870708 1.0 ug DNA
EUR 200.4

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6504006 1.0 ug DNA
EUR 200.4

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K6504007 1.0 ug DNA
EUR 200.4

Fam129b sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K6504008 1.0 ug DNA
EUR 200.4

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 546
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 6837.60
  • EUR 3613.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 518.4
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-ZNF660 antibody

44742-100ul 100ul
EUR 302.4

Anti-ZNF660 antibody

44742-50ul 50ul
EUR 224.4

Anti-CCV Antibody

10-2789 1 mg
EUR 217.2
Description: Anti-Canine Corona Virus Antibody

Anti-CCV Antibody

10-2790 1 mg
EUR 217.2
Description: Anti-Canine Corona Virus Antibody

Anti-CDV antibody

10-2791 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2792 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2793 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2794 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CPV Antibody

10-2795 500 uig
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-CPV Antibody

10-2796 500 ug
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-CPV Antibody

10-2797 500 ug
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-C.CRP antibody

10-2798 500 ug
EUR 165.6
Description: Anti-Canine CRP antibody

Anti-C.CRP antibody

10-2799 500 ug
EUR 165.6
Description: Anti-Canine CRP antibody

Anti-CHW antibody

10-2800 1 mg
EUR 198
Description: Anti-Canine Heartworm antibody

Anti-FeLV antibody

10-2801 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-FeLV antibody

10-2802 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-FeLV antibody

10-2803 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-PGI antibody

10-2806 1 mg
EUR 502.8
Description: Anti-PGI recombinant antibody

Anti-PGI antibody

10-2807 1 mg
EUR 502.8
Description: Anti-PGI recombinant antibody

Anti-PGII antibody

10-2808 1 mg
EUR 502.8
Description: Anti-PGII recombinant antibody

Anti-PGII antibody

10-2809 1 mg
EUR 502.8
Description: Anti-PGII recombinant antibody

Anti-CHW antibody

10-2810 1 mg
EUR 198
Description: Anti-CHW monoclonal antibody

Anti-Giardia antibody

10-2811 1 mg
EUR 198
Description: Anti-Giardia monoclonal antibody

Anti-Giardia antibody

10-2812 1 mg
EUR 198
Description: Anti-Giardia monoclonal antibody

Anti-TAP1 Antibody

A01123 100ul
EUR 476.4
Description: Rabbit Polyclonal TAP1 Antibody. Validated in IP, IHC, WB and tested in Human, Rat.

Anti-CHD4 Antibody

A01125 100ul
EUR 476.4
Description: Rabbit Polyclonal CHD4 Antibody. Validated in IF, IHC and tested in Human, Mouse.

Anti-NRF1 Antibody

A01129-2 100ug/vial
EUR 400.8

Anti-MEF2C Antibody

A01131-1 100ug/vial
EUR 400.8

Anti-SCN4A Antibody

A01138 100ul
EUR 476.4
Description: Rabbit Polyclonal SCN4A Antibody. Validated in WB and tested in Human.

Anti-MTR Antibody

A01140-2 100ug/vial
EUR 400.8

Anti-IL12B Antibody

A01152-2 100ug/vial
EUR 352.8

Anti-IL12B Antibody

A01152-3 100ug/vial
EUR 400.8

Anti-IL12B Antibody

A01152-4 100ug/vial
EUR 352.8

Anti-IL11 Antibody

A01160-1 100ug/vial
EUR 352.8

Anti-Bak Antibody

A01163 200ug
EUR 626.4
Description: Rabbit Polyclonal Bak Antibody. Validated in IP, IF, IHC, WB and tested in Human.

Anti-PGF Antibody

A01164-1 100ug/vial
EUR 352.8

Anti-PGF Antibody

A01164-2 100ug/vial
EUR 352.8

Anti-CD201 Antibody

A01166 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CD201 Antibody (PROCR) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-SERCA2 Antibody

A01176 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for SERCA2 Antibody (ATP2A2) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-XPA Antibody

A01182 100ul
EUR 476.4
Description: Rabbit Polyclonal XPA Antibody. Validated in IHC, WB and tested in Human.

Anti-XPA Antibody

A01182-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for XPA Antibody (XPA) detection.tested for WB in Human, Mouse.

As well as, we confirmed that Toc-HDO concentrating on miR-126 was delivered into BECs extra effectively than the guardian antimiR in ischemic mind, and that it was delivered extra successfully in ischemic mind than non-ischemic mind of this mannequin mice. Our research highlights the potential of this know-how as a brand new medical therapeutic possibility for ischemic stroke.

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