Oligonucleotides fluorescence in situ hybridization (Oligo-FISH) is an rising know-how and is a crucial device in analysis areas comparable to detection of chromosome variation, identification of allopolyploid, and deciphering of three-dimensional (3D) genome constructions. Primarily based on the demand for extremely environment friendly oligo probes for oligo-FISH experiments, growing numbers of instruments have been developed for probe design lately. Out of date oligonucleotide design instruments have been tailored for oligo-FISH probe design due to their comparable issues.
With the event of DNA sequencing and large-scale synthesis, novel instruments have been designed to extend the specificity of designed oligo probes and allow genome-scale oligo probe design, which has tremendously improved the appliance of single copy oligo-FISH. Regardless of this, few research have launched the event of the oligo-FISH probe design instruments and their utility in FISH experiments systematically. Apart from, a complete comparability and analysis is missing for the out there instruments. On this evaluation, we offer an outline of the oligo-FISH probe design course of, summarize the event and utility of the out there instruments, consider a number of state-of-art instruments, and finally present steering for single copy oligo-FISH probe design.
At the moment there’s an pressing must develop antiviral medicine and alleviate present COVID-19 pandemic. Though many candidates have been developed, we right here designed and constructed chimeric oligonucleotides comprising a 2′-OMe modified antisense oligonucleotide and a 5′-phosphorylated 2′-5′ poly(A) 4 (4A 2-5 ) to degrade envelope and spike RNAs of SARS-CoV-2. The oligonucleotide was used for looking and recognizing goal viral RNA sequence, and the conjugated 4A 2-5 was used for guided ribonuclease L (RNase L) activation to sequence-specifically degrade viral RNAs.
Since RNase L can potently cleave single strand RNA throughout innate antiviral response, degradation efficiencies with these chimeras have been twice as a lot as solely 2′-OMe modified oligonucleotides for each SARS-CoV-2 RNA targets. In pseudovirus an infection fashions, one of many chimeras concentrating on spike RNA achieved potent and broad-spectrum inhibition of SARS-CoV-2 and its N501Y and/or ΔH69/ΔV70 mutants.
Simultaneous quantitation of inorganic ions in oligonucleotides utilizing mixed-mode liquid chromatography coupled with a charged aerosol detector
The quantities of inorganic ions (e.g. sodium, potassium, magnesium, calcium, chloride, and phosphate) in intrathecally administered oligonucleotide drug merchandise should be managed with a view to meet the ultimate goal formulation composition. Throughout course of growth, these ions are measured to make sure the answer composition doesn’t change throughout purification or drug product compounding and to make sure the ultimate drug product targets are achieved.
A quantitative methodology for ion evaluation in antisense oligonucleotide (ASO) medicine was developed by mixed-mode anion trade/cation exchange-hydrophilic interplay liquid chromatography (AEX/CEX-HILIC) with a charged aerosol detector (CAD). This thirteen-minute methodology measures monovalent and multivalent cations and anions concurrently. LC separation circumstances, CAD parameters, and pattern preparation have been judiciously optimized to make sure that the strategy is restricted, correct, exact, linear, strong, and rugged. With this LC-CAD method, ion evaluation for oligonucleotide medicine may be carried out in most analytical labs to help drug growth.
Antisense Oligonucleotide-Mediated Discount of HDAC6 Does Not Scale back Tau Pathology in P301S Tau Transgenic Mice
Acetylation of tau protein is dysregulated in Alzheimer’s Illness (AD). It has been proposed that acetylation of particular websites within the KXGS motif of tau can regulate phosphorylation of close by residues and scale back the propensity of tau to mixture. Histone deacetylase 6 (HDAC6) is a cytoplasmic enzyme concerned in deacetylation of a number of targets, together with tau, and it has been steered that inhibition of HDAC6 would enhance tau acetylation on the KXGS motifs and thus might current a viable therapeutic method to deal with AD.
To instantly take a look at the contribution of HDAC6 to tau pathology, we intracerebroventricularly injected an antisense oligonucleotide (ASO) directed towards HDAC6 mRNA into brains of P301S tau mice (PS19 mannequin), which resulted in a 70% knockdown of HDAC6 protein within the mind. Regardless of a sturdy lower in ranges of HDAC6, no enhance in tau acetylation was noticed. Moreover, no change of tau phosphorylation or tau aggregation was detected upon the knockdown of HDAC6. We conclude that HDAC6 doesn’t affect tau pathology in PS19 mice.
Efficient silencing of miR-126 after ischemic stroke via intravenous α-tocopherol-conjugated heteroduplex oligonucleotide in mice
Mind endothelial cells (BECs) are concerned within the pathogenesis of ischemic stroke. Lately, a number of microRNAs (miRNAs) in BECs have been reported to manage the endothelial operate in ischemic mind. Due to this fact, modulation of miRNAs in BECs by a therapeutic oligonucleotide to inhibit miRNA (antimiR) might be a helpful technique for treating ischemic stroke. Nevertheless, few makes an attempt have been made to realize this technique through systemic route because of lack of environment friendly delivery-method towards BECs.
Right here, we have now developed a brand new know-how for delivering an antimiR into BECs and silencing miRNAs in BECs, utilizing a mouse ischemic stroke mannequin. We designed a heteroduplex oligonucleotide, comprising an antimiR towards miRNA-126 (miR-126) often called the endothelial-specific miRNA and its complementary RNA, conjugated to α-tocopherol as a supply ligand (Toc-HDO concentrating on miR-126). Intravenous administration of Toc-HDO concentrating on miR-126 remarkably suppressed miR-126 expression in ischemic mind of the mannequin mice.
FAM129B Polyclonal Antibody |
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E-AB-92187-60uL | Elabscience Biotech | 60uL | EUR 200 |
Description: Unconjugated |
FAM129B Polyclonal Antibody |
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E-AB-92187-each | Elabscience Biotech | each | Ask for price |
Description: Unconjugated |
FAM129B Antibody / MINERVA / NIBAN2 |
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RQ6569 | NSJ Bioreagents | 100ug | EUR 356.15 |
Description: FAM129B/Niban-like protein 1 (family with sequence similarity 129, member B) belongs to a poorly characterized family of Niban proteins that also includes FAM129A/Niban and FAM129C/Niban-like protein 2. FAM129A/Niban is implicated in the ER stress response and is upregulated at the protein level in thyroid carcinoma. FAM129C/Niban-like protein 2 is preferentially expressed in B-cells and is one of five biomarkers upregulated in whole blood from patients with colorectal carcinoma. FAM129B is broadly expressed and has been shown to be a downstream target of B-Raf in melanoma cells. Though FAM129B does not appear to regulate cell growth and division, phosphorylation of FAM129B by B-Raf is essential for the invasive potential of melanoma and non-melanoma cell lines. Deletion of FAM129B in melanoma cells significantly impairs B-Raf/MEK/Erk-dependent invasion into the extracellular matrix. |
FAM129B (Ab-712) Antibody |
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CSB-PA998601- | Cusabio | each | EUR 402 |
Description: A polyclonal antibody against FAM129B (Ab-712). Recognizes FAM129B (Ab-712) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200 |
FAM129B (Ab-712) Antibody |
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CSB-PA998601-100ul | Cusabio | 100ul | EUR 379.2 |
Description: A polyclonal antibody against FAM129B (Ab-712). Recognizes FAM129B (Ab-712) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200 |
Rabbit Anti-Human FAM129B (aa 710-714) Polyclonal Antibody |
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CPB-1199RH | Creative Diagnostics | 100 ul | EUR 552 |
ARP62735_P050-25UL - FAM129B Antibody - C-terminal region |
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ARP62735_P050-25UL | Aviva Systems Biology | 25ul | EUR 99 |
ARP62735_P050 - FAM129B antibody - C-terminal region (ARP62735_P050) |
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ARP62735_P050 | Aviva Systems Biology | 100ul | EUR 389 |
Fam129b/ Rat Fam129b ELISA Kit |
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ELI-45712r | Lifescience Market | 96 Tests | EUR 1063.2 |
Family With Sequence Similarity 129, Member B (FAM129B) Antibody |
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abx232965-100ug | Abbexa | 100 ug | EUR 610.8 |
Family with Sequence Similarity 129, Member B (FAM129B) Antibody |
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abx331409-100ul | Abbexa | 100 ul | EUR 510 |
Human Protein FAM129B (FAM129B) ELISA Kit |
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abx387257-96tests | Abbexa | 96 tests | EUR 1093.2 |
FAM129B siRNA |
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20-abx916030 | Abbexa |
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FAM129B siRNA |
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20-abx916031 | Abbexa |
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FAM129B siRNA |
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20-abx901842 | Abbexa |
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FAM129B ELISA KIT|Human |
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EF009517 | Lifescience Market | 96 Tests | EUR 826.8 |
Rat FAM129B shRNA Plasmid |
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20-abx990325 | Abbexa |
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Mouse FAM129B shRNA Plasmid |
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20-abx981593 | Abbexa |
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Human FAM129B shRNA Plasmid |
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20-abx962121 | Abbexa |
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anti- FAM160B1 antibody |
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FNab02970 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM160B1 |
anti- FAM160B2 antibody |
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FNab02971 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM160B2 |
anti- FAM111B antibody |
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FNab02954 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM111B |
anti- FAM116B antibody |
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FNab02956 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM116B |
anti- FAM117B antibody |
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FNab02957 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM117B |
anti- FAM118B antibody |
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FNab02958 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM118B |
anti- FAM124B antibody |
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FNab02961 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against FAM124B |
anti- FAM127B antibody |
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FNab02963 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM127B |
anti- FAM168B antibody |
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FNab02973 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM168B |
anti- FAM186B antibody |
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FNab02976 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM186B |
FAM129B Recombinant Protein (Rat) |
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RP200402 | ABM | 100 ug | Ask for price |
FAM129B Recombinant Protein (Human) |
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RP057474 | ABM | 100 ug | Ask for price |
FAM129B Recombinant Protein (Mouse) |
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RP132935 | ABM | 100 ug | Ask for price |
anti- FAM40B antibody |
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FNab02984 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM40B |
anti- FAM46B antibody |
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FNab02985 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM46B |
anti- FAM49B antibody |
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FNab02987 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM49B |
anti- FAM57B antibody |
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FNab02989 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM57B |
anti- FAM65B antibody |
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FNab02991 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM65B |
anti- FAM84B antibody |
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FNab02997 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against FAM84B |
anti- FAM96B antibody |
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FNab03000 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM96B |
anti- FAM98B antibody |
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FNab03001 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against FAM98B |
Fam129b (untagged) - Mouse family with sequence similarity 129, member B (Fam129b), (10ug) |
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MC203028 | Origene Technologies GmbH | 10 µg | Ask for price |
Fam129b ORF Vector (Rat) (pORF) |
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ORF066802 | ABM | 1.0 ug DNA | EUR 607.2 |
Fam129b (Myc-DDK-tagged) - Mouse family with sequence similarity 129, member B (Fam129b) |
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MR210452 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B ORF Vector (Human) (pORF) |
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ORF019159 | ABM | 1.0 ug DNA | EUR 486 |
Fam129b ORF Vector (Mouse) (pORF) |
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ORF044313 | ABM | 1.0 ug DNA | EUR 607.2 |
Human FAM129B knockout cell line |
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ABC-KH5089 | AcceGen | 1 vial | Ask for price |
Description: Human FAM129B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
Human FAM129B knockdown cell line |
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ABC-KD5089 | AcceGen | 1 vial | Ask for price |
Description: Human FAM129B knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
Human FAM129B Protein Lysate 20ug |
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IHUFAM129BPLLY20UG | Innovative research | each | EUR 361 |
Description: Human FAM129B Protein Lysate 20ug |
Anti-FAM129B antibody |
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PAab02965 | Lifescience Market | 100 ug | EUR 463.2 |
Fam129b (untagged ORF) - Rat family with sequence similarity 129, member B (Fam129b), (10 ug) |
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RN215551 | Origene Technologies GmbH | 10 µg | Ask for price |
OCOA08502-20UG - FAM129B Protein Lysate |
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OCOA08502-20UG | Aviva Systems Biology | 20ug | EUR 269 |
FAM129B (untagged)-Human family with sequence similarity 129, member B (FAM129B), transcript variant 2 |
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SC302844 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B (untagged)-Human family with sequence similarity 129, member B (FAM129B), transcript variant 1 |
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SC305057 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B (GFP-tagged) - Human family with sequence similarity 129, member B (FAM129B), transcript variant 1 |
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RG220901 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B (GFP-tagged) - Human family with sequence similarity 129, member B (FAM129B), transcript variant 2 |
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RG221268 | Origene Technologies GmbH | 10 µg | Ask for price |
Fam129b (Myc-DDK-tagged ORF) - Rat family with sequence similarity 129, member B (Fam129b), (10 ug) |
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RR215551 | Origene Technologies GmbH | 10 µg | Ask for price |
Fam129b sgRNA CRISPR Lentivector set (Rat) |
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K6504001 | ABM | 3 x 1.0 ug | EUR 406.8 |
FAM129B sgRNA CRISPR Lentivector set (Human) |
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K0745701 | ABM | 3 x 1.0 ug | EUR 406.8 |
Fam129b sgRNA CRISPR Lentivector set (Mouse) |
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K4870701 | ABM | 3 x 1.0 ug | EUR 406.8 |
Lenti ORF clone of Fam129b (mGFP-tagged) - Mouse family with sequence similarity 129, member B (Fam129b) |
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MR210452L4 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B (Myc-DDK-tagged)-Human family with sequence similarity 129, member B (FAM129B), transcript variant 2 |
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RC221268 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B (Myc-DDK-tagged)-Human family with sequence similarity 129, member B (FAM129B), transcript variant 1 |
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RC220901 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B 3'UTR GFP Stable Cell Line |
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TU057555 | ABM | 1.0 ml | EUR 1825.2 |
Fam129b 3'UTR GFP Stable Cell Line |
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TU254268 | ABM | 1.0 ml | Ask for price |
Fam129b 3'UTR GFP Stable Cell Line |
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TU156140 | ABM | 1.0 ml | Ask for price |
Lenti ORF clone of Fam129b (Myc-DDK-tagged) - Mouse family with sequence similarity 129, member B (Fam129b) |
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MR210452L3 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B Protein Vector (Rat) (pPM-C-HA) |
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PV267208 | ABM | 500 ng | EUR 1399.2 |
FAM129B Protein Vector (Rat) (pPB-C-His) |
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PV267206 | ABM | 500 ng | EUR 1399.2 |
FAM129B Protein Vector (Rat) (pPB-N-His) |
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PV267207 | ABM | 500 ng | EUR 1399.2 |
FAM129B Protein Vector (Rat) (pPM-C-His) |
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PV267209 | ABM | 500 ng | EUR 1399.2 |
FAM129B Protein Vector (Human) (pPM-C-HA) |
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PV076635 | ABM | 500 ng | EUR 662.4 |
FAM129B Protein Vector (Mouse) (pPM-C-HA) |
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PV177252 | ABM | 500 ng | EUR 1278 |
FAM129B Protein Vector (Human) (pPB-C-His) |
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PV076633 | ABM | 500 ng | EUR 662.4 |
FAM129B Protein Vector (Human) (pPB-N-His) |
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PV076634 | ABM | 500 ng | EUR 662.4 |
FAM129B Protein Vector (Human) (pPM-C-His) |
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PV076636 | ABM | 500 ng | EUR 662.4 |
FAM129B Protein Vector (Mouse) (pPB-C-His) |
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PV177250 | ABM | 500 ng | EUR 1278 |
FAM129B Protein Vector (Mouse) (pPB-N-His) |
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PV177251 | ABM | 500 ng | EUR 1278 |
FAM129B Protein Vector (Mouse) (pPM-C-His) |
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PV177253 | ABM | 500 ng | EUR 1278 |
Fam129b 3'UTR Luciferase Stable Cell Line |
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TU204268 | ABM | 1.0 ml | Ask for price |
FAM129B 3'UTR Luciferase Stable Cell Line |
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TU007555 | ABM | 1.0 ml | EUR 1825.2 |
Fam129b 3'UTR Luciferase Stable Cell Line |
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TU106140 | ABM | 1.0 ml | Ask for price |
Fam129b sgRNA CRISPR Lentivector (Rat) (Target 1) |
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K6504002 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129b sgRNA CRISPR Lentivector (Rat) (Target 2) |
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K6504003 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129b sgRNA CRISPR Lentivector (Rat) (Target 3) |
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K6504004 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129B sgRNA CRISPR Lentivector (Human) (Target 1) |
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K0745702 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129B sgRNA CRISPR Lentivector (Human) (Target 2) |
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K0745703 | ABM | 1.0 ug DNA | EUR 184.8 |
FAM129B sgRNA CRISPR Lentivector (Human) (Target 3) |
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K0745704 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129b sgRNA CRISPR Lentivector (Mouse) (Target 1) |
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K4870702 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129b sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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K4870703 | ABM | 1.0 ug DNA | EUR 184.8 |
Fam129b sgRNA CRISPR Lentivector (Mouse) (Target 3) |
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K4870704 | ABM | 1.0 ug DNA | EUR 184.8 |
Lenti ORF particles, Fam129b (GFP-tagged) - Mouse family with sequence similarity 129, member B (Fam129b), 200ul, >10^7 TU/mL |
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MR210452L4V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF clone of Fam129b (mGFP-tagged ORF) - Rat family with sequence similarity 129, member B (Fam129b), (10 ug) |
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RR215551L4 | Origene Technologies GmbH | 10 µg | Ask for price |
AAP62735-100UG - FAM129B Peptide - C-terminal region |
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AAP62735-100UG | Aviva Systems Biology | 100ug | EUR 99 |
Lenti ORF particles, Fam129b (GFP-tagged ORF) - Rat family with sequence similarity 129, member B (Fam129b), 200ul, >10^7 TU/mL |
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RR215551L4V | Origene Technologies GmbH | 200 µl | Ask for price |
Mouse Niban- like protein 1, Fam129b ELISA KIT |
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ELI-35343m | Lifescience Market | 96 Tests | EUR 1038 |
Human Niban- like protein 1, FAM129B ELISA KIT |
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ELI-13124h | Lifescience Market | 96 Tests | EUR 988.8 |
Lenti-ORF clone of FAM129B (mGFP-tagged)-Human family with sequence similarity 129, member B (FAM129B), transcript variant 2 |
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RC221268L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF clone of Fam129b (Myc-DDK-tagged ORF) - Rat family with sequence similarity 129, member B (Fam129b), (10 ug) |
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RR215551L3 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, Fam129b (Myc-DDK-tagged) - Mouse family with sequence similarity 129, member B (Fam129b), 200ul, >10^7 TU/mL |
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MR210452L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Human Niban-like protein 1 (FAM129B) ELISA Kit |
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RK11556 | Abclonal | 96T | EUR 280 |
Lenti ORF particles, Fam129b (Myc-DDK-tagged ORF) - Rat family with sequence similarity 129, member B (Fam129b), 200ul, >10^7 TU/mL |
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RR215551L3V | Origene Technologies GmbH | 200 µl | Ask for price |
FAM129B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
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LV667033 | ABM | 1.0 ug DNA | EUR 1626 |
FAM129B Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC) |
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LV667037 | ABM | 1.0 ug DNA | EUR 1626 |
Lenti-ORF clone of FAM129B (Myc-DDK-tagged)-Human family with sequence similarity 129, member B (FAM129B), transcript variant 2 |
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RC221268L3 | Origene Technologies GmbH | 10 µg | Ask for price |
FAM129B Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a) |
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LV667038 | ABM | 1.0 ug DNA | EUR 1626 |
Anti-FAM129B (Ser679, 683) antibody |
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STJ120070 | St John's Laboratory | 100 µl | EUR 631.2 |
Anti-FAM129B Rabbit Polyclonal Antibody |
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TA323380 | Origene Technologies GmbH | 100 µl | Ask for price |
FAM160B2 Antibody |
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ABD7245 | Lifescience Market | 100 ug | EUR 525.6 |
FAM160B2 antibody |
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38631-100ul | SAB | 100ul | EUR 302.4 |
FAM160B2 Antibody |
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E19-7245 | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
FAM149B1 Antibody |
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1-CSB-PA839295LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM149B1. Recognizes FAM149B1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
FAM160B2 Antibody |
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DF7245 | Affbiotech | 200ul | EUR 420 |
FAM160B2 Antibody |
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DF7245-100ul | Affinity Biosciences | 100ul | EUR 280 |
FAM160B2 Antibody |
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DF7245-200ul | Affinity Biosciences | 200ul | EUR 350 |
FAM160B2 Antibody |
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E93192 | EnoGene | 100μg | EUR 255 |
Description: Available in various conjugation types. |
FAM108B1 Antibody |
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E314567 | EnoGene | 100ug/200ul | EUR 295 |
Description: Available in various conjugation types. |
FAM149B1 Antibody |
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E310360 | EnoGene | 200ul | EUR 275 |
Description: Available in various conjugation types. |
FAM160B1 Antibody |
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E311254 | EnoGene | 200ul | EUR 275 |
Description: Available in various conjugation types. |
FAM160B2 antibody |
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70R-17214 | Fitzgerald | 50 ul | EUR 289 |
Description: Rabbit polyclonal FAM160B2 antibody |
FAM108B1 antibody |
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70R-3168 | Fitzgerald | 50 ug | EUR 560.4 |
Description: Rabbit polyclonal FAM108B1 antibody raised against the middle region of FAM108B1 |
FAM160B1 antibody |
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70R-4079 | Fitzgerald | 50 ug | EUR 467 |
Description: Rabbit polyclonal FAM160B1 antibody raised against the N terminal of FAM160B1 |
FAM160B2 Antibody |
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1-CSB-PA008108GA01HU | Cusabio |
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Description: A polyclonal antibody against FAM160B2. Recognizes FAM160B2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
FAM160B1 Antibody |
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1-CSB-PA726129LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM160B1. Recognizes FAM160B1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
FAM108B1 Antibody |
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GWB-MU529G | GenWay Biotech | 50ug | Ask for price |
FAM160B1 Antibody |
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GWB-MU847A | GenWay Biotech | 50ug | Ask for price |
FAM188B2 Antibody |
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GWB-MV272B | GenWay Biotech | 50ug | Ask for price |
FAM193B Antibody |
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6941-002mg | ProSci | 0.02 mg | EUR 206.18 |
Description: FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans. |
FAM193B Antibody |
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6941-01mg | ProSci | 0.1 mg | EUR 523.7 |
Description: FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans. |
FAM186B Antibody |
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47320 | SAB | 100ul | EUR 319 |
FAM186B Antibody |
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47320-100ul | SAB | 100ul | EUR 302.4 |
FAM107B Antibody |
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47434 | SAB | 100ul | EUR 319 |
FAM107B Antibody |
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47434-100ul | SAB | 100ul | EUR 302.4 |
FAM111B Antibody |
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47538 | SAB | 100ul | EUR 319 |
FAM111B Antibody |
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47538-100ul | SAB | 100ul | EUR 302.4 |
FAM155B Antibody |
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47540 | SAB | 100ul | EUR 319 |
FAM155B Antibody |
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47540-100ul | SAB | 100ul | EUR 302.4 |
FAM177B Antibody |
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47541 | SAB | 100ul | EUR 319 |
FAM177B Antibody |
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47541-100ul | SAB | 100ul | EUR 302.4 |
FAM110B Antibody |
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46561 | SAB | 100ul | EUR 319 |
FAM110B Antibody |
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46561-100ul | SAB | 100ul | EUR 302.4 |
FAM213B Antibody |
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46564 | SAB | 100ul | EUR 319 |
FAM213B Antibody |
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46564-100ul | SAB | 100ul | EUR 302.4 |
FAM151B Antibody |
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1-CSB-PA740923LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM151B. Recognizes FAM151B from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
FAM109B Antibody |
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1-CSB-PA753688LA01HU | Cusabio |
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Description: A polyclonal antibody against FAM109B. Recognizes FAM109B from Human. This antibody is Unconjugated. Tested in the following application: ELISA |
As well as, we confirmed that Toc-HDO concentrating on miR-126 was delivered into BECs extra effectively than the guardian antimiR in ischemic mind, and that it was delivered extra successfully in ischemic mind than non-ischemic mind of this mannequin mice. Our research highlights the potential of this know-how as a brand new medical therapeutic possibility for ischemic stroke.