Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing

Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing

Locked nucleic acid-modified antisense oligonucleotides (ASOs) can obtain strongly totally different levels of goal knockdown regardless of having comparable biophysical properties and 100% homology with their goal. The determinants for this statement stay largely unknown. We used multi-specific ASOs which have 100% sequence complementarity with a typical goal (IDO1) and a special variety of numerous targets and investigated their impact on gene expression in a cell line by RNA-sequencing. We noticed a major larger likelihood for downregulation of lengthy genes in comparison with brief genes, of genes with excessive in comparison with decrease expression, and of genes which have a couple of binding web site for the respective ASO.

By investigating the expression of genes which have binding websites for a couple of ASO we recognized the person binding web site being an vital determinant for exercise. Underneath the chosen experimental circumstances we have now not seen indications that availability of RNase H is a limiting issue because the variety of degraded goal RNA molecules correlated considerably with the variety of predicted goal RNA molecules. Taken collectively, through the use of multi-specific ASOs as software compounds we recognized determinants for ASO exercise that may be considered to enhance the choice technique of extremely potent and selective ASOs sooner or later.

Liver-Focused Supply of Oligonucleotides with N-Acetylgalactosamine Conjugation

The potential therapeutic utility of oligonucleotides (ONs) that selectively suppress goal genes by means of antisense and RNA interference mechanisms has attracted nice consideration. The medical functions of ONs have overcome a number of obstacles and turn into one of the crucial energetic areas for the event of novel therapeutics. To attain environment friendly and particular mobile internalization, conjugation of a wide range of purposeful teams to ONs has been the topic of intensive investigations over the previous decade. Amongst them, a promising liver-targeted N-acetylgalactosamine (GalNAc) ligand has been evaluated in a number of preclinical and medical trials for enhancing the mobile uptake and tissue particular supply of ONs.

GalNAc-based supply depends on the truth that liver hepatocytes abundantly and particularly categorical the asialoglycoprotein receptor that binds and uptakes circulating glycoproteins by way of receptor-mediated endocytosis. Lately, encouraging progress has been made within the discipline of GalNAc conjugates. This assessment goals to supply an summary of GalNAc-mediated liver-targeted supply of small interfering RNA and antisense oligonucleotides, and the immense effort in addition to current advances within the improvement of GalNAc-conjugated brokers are described.

Molecular analysis of viral genotyping devoid of polymerase chain response (PCR) amplification in medical cohorts has hitherto been difficult. Right here we current a simplified molecular diagnostic technique for direct genotyping of hepatitis C virus (HCV) 1 and three (prevalent worldwide) utilizing a mix of rationally designed genotype-specific antisense oligonucleotides (ASOs) and plasmonic gold nanoparticles. The ASOs particular to genotypes 1 and three have been designed from the nonstructural area 5A (NS5A) of the viral genome utilizing the ClustalW a number of sequence alignment software.

A complete of 79 medical samples together with 18 HCV genotype 1, 18 HCV genotype 3, one HIV constructive, one HBV constructive, and 41 wholesome controls have been examined towards each the designed ASOs. The research reveals 100% specificity and sensitivity with the employed samples and thereby opens up new avenues for PCR-free direct genotyping of different viruses as nicely, by means of the rational design of ASOs.

Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing

A extremely potent lead ASO, effectively delivered by free uptake, was capable of considerably enhance the extent of accurately spliced mRNA and fully restore the CFTR operate to wild kind ranges in cells from a homozygote affected person. This ASO led to CFTR operate with a median of 43% of untamed kind ranges in cells from varied heterozygote sufferers. Optimized effectivity of the lead ASO was additional obtained with 2′-Methoxy Ethyl modification (2’MOE). The extremely environment friendly splicing modulation and purposeful correction, achieved by free uptake of the chosen lead ASO in varied sufferers, exhibit the ASO therapeutic potential profit for CF sufferers carrying splicing mutations and is aimed to function the premise for our present medical improvement.

PaintSHOP allows the interactive design of transcriptome- and genome-scale oligonucleotide FISH experiments

Fluorescence in situ hybridization (FISH) permits researchers to visualise the spatial place and amount of nucleic acids in mounted samples. Not too long ago, appreciable progress has been made in growing oligonucleotide (oligo)-based FISH strategies which have enabled researchers to review the three-dimensional group of the genome at super-resolution and visualize the spatial patterns of gene expression for 1000’s of genes in particular person cells. Nevertheless, there are few present computational instruments to assist the bioinformatics workflows obligatory to hold out these experiments utilizing oligo FISH probes.

Right here, we introduce paint server and homology optimization pipeline (PaintSHOP), an interactive platform for the design of oligo FISH experiments. PaintSHOP allows researchers to establish probes for his or her experimental targets effectively, to include extra obligatory sequences equivalent to primer pairs and to simply generate recordsdata documenting library design. PaintSHOP democratizes and standardizes the method of designing complicated probe units for the oligo FISH neighborhood.

HIBADH antibody

70R-2475 50 ug
EUR 467
Description: Rabbit polyclonal HIBADH antibody raised against the middle region of HIBADH

HIBADH antibody

70R-2529 50 ug
EUR 467
Description: Rabbit polyclonal HIBADH antibody raised against the middle region of HIBADH

HIBADH antibody

70R-33913 100 ug
EUR 327
Description: Rabbit polyclonal HIBADH antibody

HIBADH Polyclonal Antibody

ES4600-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against HIBADH from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

HIBADH Polyclonal Antibody

ES4600-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against HIBADH from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

Anti-HIBADH antibody

STJ23942 100 µl
EUR 277
Description: This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.

Anti-HIBADH antibody

STJ11100747 100 µl
EUR 413
Description: This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.

Anti-HIBADH Antibody

A08760-1 100ul
EUR 397
Description: Rabbit Polyclonal HIBADH Antibody. Validated in IHC and tested in Human, Mouse, Rat.

HIBADH Polyclonal Antibody

ABP53601-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of HIBADH from Human, Mouse, Rat. This HIBADH antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human HIBADH at AA rangle: 250-330

HIBADH Polyclonal Antibody

ABP53601-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of HIBADH from Human, Mouse, Rat. This HIBADH antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human HIBADH at AA rangle: 250-330

HIBADH Polyclonal Antibody

ABP53601-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of HIBADH from Human, Mouse, Rat. This HIBADH antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human HIBADH at AA rangle: 250-330

Anti-HIBADH antibody

STJ93496 200 µl
EUR 197
Description: Rabbit polyclonal to HIBADH.

anti- HIBADH antibody

FNab03855 100µg
EUR 548.75
Description: Antibody raised against HIBADH

HIBADH Conjugated Antibody

C34327 100ul
EUR 397

Anti-HIBADH antibody

PAab03855 100 ug
EUR 386

Hibadh/ Rat Hibadh ELISA Kit

ELI-35175r 96 Tests
EUR 886

HIBADH siRNA

20-abx919345
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

HIBADH siRNA

20-abx919346
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

HIBADH siRNA

20-abx902458
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

anti-HIBADH

YF-PA17437 50 ug
EUR 363
Description: Mouse polyclonal to HIBADH

anti-HIBADH

YF-PA17438 100 ug
EUR 403
Description: Rabbit polyclonal to HIBADH

HIBADH Rabbit pAb

A1264-100ul 100 ul
EUR 308

HIBADH Rabbit pAb

A1264-200ul 200 ul
EUR 459

HIBADH Rabbit pAb

A1264-20ul 20 ul
EUR 183

HIBADH Rabbit pAb

A1264-50ul 50 ul
EUR 223

HIBADH Blocking Peptide

20-abx162488
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

HIBADH Blocking Peptide

DF12632-BP 1mg
EUR 195

HIBADH Blocking Peptide

33R-1292 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ARHGAP28 antibody, catalog no. 70R-3328

HIBADH Blocking Peptide

33R-10017 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HIBADH antibody, catalog no. 70R-2529

Polyclonal HIBADH Antibody (aa281-330)

APR07741G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIBADH (aa281-330). This antibody is tested and proven to work in the following applications:

Polyclonal HIBADH Antibody (N-term)

APR07742G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIBADH (N-term). This antibody is tested and proven to work in the following applications:

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

20-abx121493
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

20-abx110711
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

20-abx001170
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

20-abx014090
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

abx029841-400ul 400 ul
EUR 523

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

abx029841-80l 80 µl
EUR 286

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

20-abx214624
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

abx233855-100ug 100 ug
EUR 509

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody

20-abx326435
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Rat HIBADH shRNA Plasmid

20-abx986119
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Mouse HIBADH shRNA Plasmid

20-abx975120
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human HIBADH shRNA Plasmid

20-abx957600
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human HIBADH ELISA KIT

ELI-24677h 96 Tests
EUR 824

Mouse Hibadh ELISA KIT

ELI-49758m 96 Tests
EUR 865

Bovine HIBADH ELISA KIT

ELI-35174b 96 Tests
EUR 928

HIBADH ELISA KIT|Human

EF004545 96 Tests
EUR 689

HIBADH Recombinant Protein (Rat)

RP204542 100 ug Ask for price

HIBADH Recombinant Protein (Human)

RP062118 100 ug Ask for price

HIBADH Recombinant Protein (Mouse)

RP141443 100 ug Ask for price

Recombinant 3-Hydroxyisobutyrate Dehydrogenase (HIBADH)

4-RPG362Hu01
  • EUR 503.20
  • EUR 238.00
  • EUR 1612.00
  • EUR 604.00
  • EUR 1108.00
  • EUR 400.00
  • EUR 3880.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human 3-Hydroxyisobutyrate Dehydrogenase expressed in: E.coli

[KO Validated] HIBADH Rabbit pAb

A19871-100ul 100 ul
EUR 410

[KO Validated] HIBADH Rabbit pAb

A19871-200ul 200 ul
EUR 571

[KO Validated] HIBADH Rabbit pAb

A19871-20ul 20 ul
EUR 221

[KO Validated] HIBADH Rabbit pAb

A19871-50ul 50 ul
EUR 287

Hibadh ELISA Kit (Mouse) (OKEH02246)

OKEH02246 96 Wells
EUR 779
Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.081 ng/mL

HIBADH ELISA Kit (Human) (OKEH05594)

OKEH05594 96 Wells
EUR 662
Description: Description of target: This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.08 ng/mL

Hibadh ORF Vector (Rat) (pORF)

ORF068182 1.0 ug DNA
EUR 506

Hibadh ORF Vector (Mouse) (pORF)

ORF047149 1.0 ug DNA
EUR 506

HIBADH ORF Vector (Human) (pORF)

ORF020707 1.0 ug DNA
EUR 405

Hibadh sgRNA CRISPR Lentivector set (Mouse)

K3137901 3 x 1.0 ug
EUR 339

HIBADH sgRNA CRISPR Lentivector set (Human)

K0950801 3 x 1.0 ug
EUR 339

Hibadh sgRNA CRISPR Lentivector set (Rat)

K7081501 3 x 1.0 ug
EUR 339

Human 3-Hydroxyisobutyrate Dehydrogenase (HIBADH) ELISA Kit

abx516056-96tests 96 tests
EUR 668

Rat 3-Hydroxyisobutyrate Dehydrogenase (HIBADH) ELISA Kit

abx516058-96tests 96 tests
EUR 739

Mouse 3-Hydroxyisobutyrate Dehydrogenase (HIBADH) ELISA Kit

abx254908-96tests 96 tests
EUR 739

Human 3-Hydroxyisobutyrate Dehydrogenase(HIBADH)ELISA Kit

QY-E05213 96T
EUR 361

Hibadh sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3137902 1.0 ug DNA
EUR 154

Hibadh sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3137903 1.0 ug DNA
EUR 154

Hibadh sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3137904 1.0 ug DNA
EUR 154

Rabbit 3- hydroxyisobutyrate dehydrogenase, HIBADH ELISA KIT

ELI-35047Ra 96 Tests
EUR 928

HIBADH sgRNA CRISPR Lentivector (Human) (Target 1)

K0950802 1.0 ug DNA
EUR 154

HIBADH sgRNA CRISPR Lentivector (Human) (Target 2)

K0950803 1.0 ug DNA
EUR 154

HIBADH sgRNA CRISPR Lentivector (Human) (Target 3)

K0950804 1.0 ug DNA
EUR 154

Hibadh sgRNA CRISPR Lentivector (Rat) (Target 1)

K7081502 1.0 ug DNA
EUR 154

Hibadh sgRNA CRISPR Lentivector (Rat) (Target 2)

K7081503 1.0 ug DNA
EUR 154

Hibadh sgRNA CRISPR Lentivector (Rat) (Target 3)

K7081504 1.0 ug DNA
EUR 154

HIBADH 3'UTR GFP Stable Cell Line

TU059771 1.0 ml
EUR 1394

HIBADH Protein Vector (Human) (pPB-C-His)

PV082825 500 ng
EUR 552

HIBADH Protein Vector (Human) (pPB-N-His)

PV082826 500 ng
EUR 552

HIBADH Protein Vector (Human) (pPM-C-HA)

PV082827 500 ng
EUR 552

HIBADH Protein Vector (Human) (pPM-C-His)

PV082828 500 ng
EUR 552

HIBADH Protein Vector (Rat) (pPB-C-His)

PV272726 500 ng
EUR 603

HIBADH Protein Vector (Rat) (pPB-N-His)

PV272727 500 ng
EUR 603

HIBADH Protein Vector (Rat) (pPM-C-HA)

PV272728 500 ng
EUR 603

HIBADH Protein Vector (Rat) (pPM-C-His)

PV272729 500 ng
EUR 603

HIBADH Protein Vector (Mouse) (pPB-C-His)

PV188594 500 ng
EUR 603

HIBADH Protein Vector (Mouse) (pPB-N-His)

PV188595 500 ng
EUR 603

HIBADH Protein Vector (Mouse) (pPM-C-HA)

PV188596 500 ng
EUR 603

HIBADH Protein Vector (Mouse) (pPM-C-His)

PV188597 500 ng
EUR 603

HIBADH 3'UTR Luciferase Stable Cell Line

TU009771 1.0 ml
EUR 1394

Hibadh 3'UTR GFP Stable Cell Line

TU255763 1.0 ml Ask for price

Hibadh 3'UTR Luciferase Stable Cell Line

TU205763 1.0 ml Ask for price

Hibadh 3'UTR GFP Stable Cell Line

TU159496 1.0 ml Ask for price

Hibadh 3'UTR Luciferase Stable Cell Line

TU109496 1.0 ml Ask for price

Mouse Hibadh/ 3-hydroxyisobutyrate dehydrogenase, mitochondrial ELISA Kit

E0670Mo 1 Kit
EUR 632

Human HIBADH/ 3-hydroxyisobutyrate dehydrogenase, mitochondrial ELISA Kit

E1120Hu 1 Kit
EUR 605

Mouse Hibadh(3-hydroxyisobutyrate dehydrogenase, mitochondrial) ELISA Kit

EM0557 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV682483 1.0 ug DNA
EUR 682

HIBADH Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV682487 1.0 ug DNA
EUR 682

HIBADH Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV682488 1.0 ug DNA
EUR 682

Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E02H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E02H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E02H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E09H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E09H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E09H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E08H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Canine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E08H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Canine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E08H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Canine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E01H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E01H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E01H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E03H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E03H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E03H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E07H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Porcine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E07H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Porcine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E07H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Porcine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E06H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E06H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E06H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E04H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E04H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E04H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E05H1386-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E05H1386-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit

E05H1386-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3137905 3 x 1.0 ug
EUR 376

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0950805 3 x 1.0 ug
EUR 376

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K7081505 3 x 1.0 ug
EUR 376

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3137906 1.0 ug DNA
EUR 167

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3137907 1.0 ug DNA
EUR 167

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3137908 1.0 ug DNA
EUR 167

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0950806 1.0 ug DNA
EUR 167

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0950807 1.0 ug DNA
EUR 167

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0950808 1.0 ug DNA
EUR 167

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV682484 1.0 ug DNA
EUR 682

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV682485 1.0 ug DNA
EUR 740

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV682486 1.0 ug DNA
EUR 740

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K7081506 1.0 ug DNA
EUR 167

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K7081507 1.0 ug DNA
EUR 167

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K7081508 1.0 ug DNA
EUR 167

CD11b Antibody Antibody

ABD2911 100 ug
EUR 438

H2B Antibody Antibody

AF4659 200ul
EUR 376
Description: H2B Antibody Antibody detects endogenous levels of H2B.

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 100 ug
EUR 438

Antibody

A1360-500 Ask for price

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 391

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 523

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 286

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 551

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 481

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Monoclonal NGF/proNGF Neutralizing Antibody Antibody

AMM06679G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-01mg 0,1 mg
EUR 267.5
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-1000ug 1000 ug
EUR 1282.5
Description: anti-CD22 monoclonal antibody

Anti-IgG1 Negative Control Antibody antibody

STJ16100881 1 mL
EUR 478

Anti-Noelin Antibody BIOTIN Antibody BIOTIN

STJ501938 100 µg
EUR 586

Anti-Noelin Antibody FITC Antibody FITC

STJ501939 100 µg
EUR 586

Anti-Noelin Antibody BIOTIN Antibody BIOTIN

STJ501940 100 µg
EUR 586

Anti-Noelin Antibody FITC Antibody FITC

STJ501941 100 µg
EUR 586

Antibody for Human alpha Tubulin Antibody

SPC-692D 0.1mg
EUR 354
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A390 0.1mg
EUR 401
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A488 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A565 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 565.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A594 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 594.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A633 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 633.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A655 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 655.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A680 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 680.

Now we have screened, in FRT cells expressing the 3849+10 kb C-to-T splicing mutation, ~30 2′-O-Methyl-modified phosphorothioate ASOs, focused to forestall the popularity and inclusion of a cryptic exon generated because of the mutation. The impact of extremely potent ASO candidates on the splicing sample, protein maturation and CFTR operate was additional analyzed in nicely differentiated main human nasal and bronchial epithelial cells, derived from sufferers carrying at the least one 3849+10 kb C-to-T allele.

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