Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing
Gerbil / Goat / Guinea Pig / Hamster / Helicobacter / purified / Rabbit / Real-time / Recombinant / Rhesus

Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing

- August 24, 2021 | August 25, 2021 - Johnny

Locked nucleic acid-modified antisense oligonucleotides (ASOs) can obtain strongly totally different levels of goal knockdown regardless of having comparable biophysical properties and 100% homology with their goal. The determinants for this statement stay largely unknown. We used multi-specific ASOs which have 100% sequence complementarity with a typical goal (IDO1) and a special variety of numerous targets and investigated their impact on gene expression in a cell line by RNA-sequencing. We noticed a major larger likelihood for downregulation of lengthy genes in comparison with brief genes, of genes with excessive in comparison with decrease expression, and of genes which have a couple of binding web site for the respective ASO.

By investigating the expression of genes which have binding websites for a couple of ASO we recognized the person binding web site being an vital determinant for exercise. Underneath the chosen experimental circumstances we have now not seen indications that availability of RNase H is a limiting issue because the variety of degraded goal RNA molecules correlated considerably with the variety of predicted goal RNA molecules. Taken collectively, through the use of multi-specific ASOs as software compounds we recognized determinants for ASO exercise that may be considered to enhance the choice technique of extremely potent and selective ASOs sooner or later.

Liver-Focused Supply of Oligonucleotides with N-Acetylgalactosamine Conjugation

The potential therapeutic utility of oligonucleotides (ONs) that selectively suppress goal genes by means of antisense and RNA interference mechanisms has attracted nice consideration. The medical functions of ONs have overcome a number of obstacles and turn into one of the crucial energetic areas for the event of novel therapeutics. To attain environment friendly and particular mobile internalization, conjugation of a wide range of purposeful teams to ONs has been the topic of intensive investigations over the previous decade. Amongst them, a promising liver-targeted N-acetylgalactosamine (GalNAc) ligand has been evaluated in a number of preclinical and medical trials for enhancing the mobile uptake and tissue particular supply of ONs.

GalNAc-based supply depends on the truth that liver hepatocytes abundantly and particularly categorical the asialoglycoprotein receptor that binds and uptakes circulating glycoproteins by way of receptor-mediated endocytosis. Lately, encouraging progress has been made within the discipline of GalNAc conjugates. This assessment goals to supply an summary of GalNAc-mediated liver-targeted supply of small interfering RNA and antisense oligonucleotides, and the immense effort in addition to current advances within the improvement of GalNAc-conjugated brokers are described.

Molecular analysis of viral genotyping devoid of polymerase chain response (PCR) amplification in medical cohorts has hitherto been difficult. Right here we current a simplified molecular diagnostic technique for direct genotyping of hepatitis C virus (HCV) 1 and three (prevalent worldwide) utilizing a mix of rationally designed genotype-specific antisense oligonucleotides (ASOs) and plasmonic gold nanoparticles. The ASOs particular to genotypes 1 and three have been designed from the nonstructural area 5A (NS5A) of the viral genome utilizing the ClustalW a number of sequence alignment software.

A complete of 79 medical samples together with 18 HCV genotype 1, 18 HCV genotype 3, one HIV constructive, one HBV constructive, and 41 wholesome controls have been examined towards each the designed ASOs. The research reveals 100% specificity and sensitivity with the employed samples and thereby opens up new avenues for PCR-free direct genotyping of different viruses as nicely, by means of the rational design of ASOs.

Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing

A extremely potent lead ASO, effectively delivered by free uptake, was capable of considerably enhance the extent of accurately spliced mRNA and fully restore the CFTR operate to wild kind ranges in cells from a homozygote affected person. This ASO led to CFTR operate with a median of 43% of untamed kind ranges in cells from varied heterozygote sufferers. Optimized effectivity of the lead ASO was additional obtained with 2′-Methoxy Ethyl modification (2’MOE). The extremely environment friendly splicing modulation and purposeful correction, achieved by free uptake of the chosen lead ASO in varied sufferers, exhibit the ASO therapeutic potential profit for CF sufferers carrying splicing mutations and is aimed to function the premise for our present medical improvement.

PaintSHOP allows the interactive design of transcriptome- and genome-scale oligonucleotide FISH experiments

Fluorescence in situ hybridization (FISH) permits researchers to visualise the spatial place and amount of nucleic acids in mounted samples. Not too long ago, appreciable progress has been made in growing oligonucleotide (oligo)-based FISH strategies which have enabled researchers to review the three-dimensional group of the genome at super-resolution and visualize the spatial patterns of gene expression for 1000’s of genes in particular person cells. Nevertheless, there are few present computational instruments to assist the bioinformatics workflows obligatory to hold out these experiments utilizing oligo FISH probes.

Right here, we introduce paint server and homology optimization pipeline (PaintSHOP), an interactive platform for the design of oligo FISH experiments. PaintSHOP allows researchers to establish probes for his or her experimental targets effectively, to include extra obligatory sequences equivalent to primer pairs and to simply generate recordsdata documenting library design. PaintSHOP democratizes and standardizes the method of designing complicated probe units for the oligo FISH neighborhood.

HIBADH Antibody
DF12632 200ul
EUR 420

HIBADH Antibody
1-CSB-PA006776
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against HIBADH. Recognizes HIBADH from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

HIBADH Antibody
1-CSB-PA010346GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against HIBADH. Recognizes HIBADH from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

Anti-HIBADH Antibody
A08760-1 100ul
EUR 476.4
Description: Rabbit Polyclonal HIBADH Antibody. Validated in IHC and tested in Human, Mouse, Rat.

HIBADH Polyclonal Antibody
ABP53601-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of HIBADH from Human, Mouse, Rat. This HIBADH antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human HIBADH at AA rangle: 250-330

HIBADH Polyclonal Antibody
ABP53601-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of HIBADH from Human, Mouse, Rat. This HIBADH antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human HIBADH at AA rangle: 250-330

HIBADH Polyclonal Antibody
ABP53601-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of HIBADH from Human, Mouse, Rat. This HIBADH antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human HIBADH at AA rangle: 250-330

HIBADH Conjugated Antibody
C34327 100ul
EUR 476.4

HIBADH Polyclonal Antibody
ES4600-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against HIBADH from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

HIBADH Polyclonal Antibody
ES4600-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against HIBADH from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

Anti-HIBADH antibody
PAab03855 100 ug
EUR 463.2

anti- HIBADH antibody
FNab03855 100µg
EUR 658.5
Description: Antibody raised against HIBADH

Anti-HIBADH antibody
STJ11100747 100 µl
EUR 495.6
Description: This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.

Anti-HIBADH antibody
STJ93496 200 µl
EUR 236.4
Description: Rabbit polyclonal to HIBADH.

Anti-HIBADH antibody
STJ23942 100 µl
EUR 332.4
Description: This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.

HIBADH Polyclonal Antibody
A73425-050 50 ul
EUR 377.3

HIBADH Polyclonal Antibody
A73425-100 100 ul
EUR 577.5

HIBADH Polyclonal Antibody
A73425
  • EUR 377.30
  • EUR 577.50
  • 50 ul
  • 100 ul

Hibadh/ Rat Hibadh ELISA Kit
ELI-35175r 96 Tests
EUR 1063.2

HIBADH siRNA
20-abx902458
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HIBADH siRNA
20-abx919345
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HIBADH siRNA
20-abx919346
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti-HIBADH
YF-PA17437 50 ug
EUR 435.6
Description: Mouse polyclonal to HIBADH

anti-HIBADH
YF-PA17438 100 ug
EUR 483.6
Description: Rabbit polyclonal to HIBADH

HIBADH Rabbit pAb
A1264-100ul 100 ul
EUR 369.6

HIBADH Rabbit pAb
A1264-200ul 200 ul
EUR 550.8

HIBADH Rabbit pAb
A1264-20ul 20 ul
EUR 219.6

HIBADH Rabbit pAb
A1264-50ul 50 ul
EUR 267.6

HIBADH Blocking Peptide
33R-1292 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ARHGAP28 antibody, catalog no. 70R-3328

HIBADH Blocking Peptide
33R-10017 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HIBADH antibody, catalog no. 70R-2529

HIBADH Blocking Peptide
20-abx162488
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

HIBADH Blocking Peptide
DF12632-BP 1mg
EUR 234

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
20-abx001170
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
20-abx121493
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
20-abx110711
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
20-abx014090
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
abx029841-400ul 400 ul
EUR 627.6

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
abx029841-80l 80 µl
EUR 343.2

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
20-abx326435
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
abx233855-100ug 100 ug
EUR 610.8

3-Hydroxyisobutyrate Dehydrogenase (HIBADH) Antibody
20-abx214624
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Polyclonal HIBADH Antibody (aa281-330)
APR07741G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIBADH (aa281-330). This antibody is tested and proven to work in the following applications:

Polyclonal HIBADH Antibody (N-term)
APR07742G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIBADH (N-term). This antibody is tested and proven to work in the following applications:

Human HIBADH shRNA Plasmid
20-abx957600
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse HIBADH shRNA Plasmid
20-abx975120
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Rat HIBADH shRNA Plasmid
20-abx986119
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

HIBADH ELISA KIT|Human
EF004545 96 Tests
EUR 826.8

Human HIBADH ELISA KIT
ELI-24677h 96 Tests
EUR 988.8

Bovine HIBADH ELISA KIT
ELI-35174b 96 Tests
EUR 1113.6

Mouse Hibadh ELISA KIT
ELI-49758m 96 Tests
EUR 1038

HIBADH Recombinant Protein (Rat)
RP204542 100 ug Ask for price

HIBADH Recombinant Protein (Human)
RP062118 100 ug Ask for price

HIBADH Recombinant Protein (Mouse)
RP141443 100 ug Ask for price

[KO Validated] HIBADH Rabbit pAb
A19871-100ul 100 ul
EUR 492

[KO Validated] HIBADH Rabbit pAb
A19871-200ul 200 ul
EUR 685.2

[KO Validated] HIBADH Rabbit pAb
A19871-20ul 20 ul
EUR 265.2

[KO Validated] HIBADH Rabbit pAb
A19871-50ul 50 ul
EUR 344.4

HIBADH ELISA Kit (Human) (OKEH05594)
OKEH05594 96 Wells
EUR 794.4
Description: Description of target: This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.08 ng/mL

Hibadh ORF Vector (Rat) (pORF)
ORF068182 1.0 ug DNA
EUR 607.2

Hibadh ELISA Kit (Mouse) (OKEH02246)
OKEH02246 96 Wells
EUR 934.8
Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.081 ng/mL

HIBADH ORF Vector (Human) (pORF)
ORF020707 1.0 ug DNA
EUR 486

Hibadh ORF Vector (Mouse) (pORF)
ORF047149 1.0 ug DNA
EUR 607.2

Recombinant 3-Hydroxyisobutyrate Dehydrogenase (HIBADH)
4-RPG362Hu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human 3-Hydroxyisobutyrate Dehydrogenase expressed in: E.coli

Hibadh sgRNA CRISPR Lentivector set (Rat)
K7081501 3 x 1.0 ug
EUR 406.8

HIBADH sgRNA CRISPR Lentivector set (Human)
K0950801 3 x 1.0 ug
EUR 406.8

Hibadh sgRNA CRISPR Lentivector set (Mouse)
K3137901 3 x 1.0 ug
EUR 406.8

Mouse 3-Hydroxyisobutyrate Dehydrogenase (HIBADH) ELISA Kit
abx254908-96tests 96 tests
EUR 886.8

Human 3-Hydroxyisobutyrate Dehydrogenase (HIBADH) ELISA Kit
abx516056-96tests 96 tests
EUR 801.6

Rat 3-Hydroxyisobutyrate Dehydrogenase (HIBADH) ELISA Kit
abx516058-96tests 96 tests
EUR 886.8

Rabbit 3- hydroxyisobutyrate dehydrogenase, HIBADH ELISA KIT
ELI-35047Ra 96 Tests
EUR 1113.6

Hibadh sgRNA CRISPR Lentivector (Rat) (Target 1)
K7081502 1.0 ug DNA
EUR 184.8

Hibadh sgRNA CRISPR Lentivector (Rat) (Target 2)
K7081503 1.0 ug DNA
EUR 184.8

Hibadh sgRNA CRISPR Lentivector (Rat) (Target 3)
K7081504 1.0 ug DNA
EUR 184.8

HIBADH sgRNA CRISPR Lentivector (Human) (Target 1)
K0950802 1.0 ug DNA
EUR 184.8

HIBADH sgRNA CRISPR Lentivector (Human) (Target 2)
K0950803 1.0 ug DNA
EUR 184.8

HIBADH sgRNA CRISPR Lentivector (Human) (Target 3)
K0950804 1.0 ug DNA
EUR 184.8

Hibadh sgRNA CRISPR Lentivector (Mouse) (Target 1)
K3137902 1.0 ug DNA
EUR 184.8

Hibadh sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3137903 1.0 ug DNA
EUR 184.8

Hibadh sgRNA CRISPR Lentivector (Mouse) (Target 3)
K3137904 1.0 ug DNA
EUR 184.8

HIBADH Protein Vector (Human) (pPB-C-His)
PV082825 500 ng
EUR 662.4

HIBADH Protein Vector (Human) (pPB-N-His)
PV082826 500 ng
EUR 662.4

HIBADH Protein Vector (Human) (pPM-C-HA)
PV082827 500 ng
EUR 662.4

HIBADH Protein Vector (Human) (pPM-C-His)
PV082828 500 ng
EUR 662.4

HIBADH Protein Vector (Mouse) (pPB-C-His)
PV188594 500 ng
EUR 723.6

HIBADH Protein Vector (Mouse) (pPB-N-His)
PV188595 500 ng
EUR 723.6

HIBADH Protein Vector (Mouse) (pPM-C-HA)
PV188596 500 ng
EUR 723.6

HIBADH Protein Vector (Mouse) (pPM-C-His)
PV188597 500 ng
EUR 723.6

HIBADH Protein Vector (Rat) (pPB-C-His)
PV272726 500 ng
EUR 723.6

HIBADH Protein Vector (Rat) (pPB-N-His)
PV272727 500 ng
EUR 723.6

HIBADH Protein Vector (Rat) (pPM-C-HA)
PV272728 500 ng
EUR 723.6

HIBADH Protein Vector (Rat) (pPM-C-His)
PV272729 500 ng
EUR 723.6

Human 3-Hydroxyisobutyrate Dehydrogenase(HIBADH)ELISA Kit
QY-E05213 96T
EUR 433.2

Hibadh 3'UTR GFP Stable Cell Line
TU255763 1.0 ml Ask for price

HIBADH 3'UTR GFP Stable Cell Line
TU059771 1.0 ml
EUR 1672.8

Hibadh 3'UTR Luciferase Stable Cell Line
TU205763 1.0 ml Ask for price

Hibadh 3'UTR Luciferase Stable Cell Line
TU109496 1.0 ml Ask for price

Hibadh 3'UTR GFP Stable Cell Line
TU159496 1.0 ml Ask for price

HIBADH 3'UTR Luciferase Stable Cell Line
TU009771 1.0 ml
EUR 1672.8

Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E06H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E06H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E06H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E04H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E04H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E04H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E01H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E01H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E01H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E03H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E03H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E03H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Hibadh(3-hydroxyisobutyrate dehydrogenase, mitochondrial) ELISA Kit
EM0557 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E07H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E07H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E07H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E09H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E09H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E09H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Hibadh/ 3-hydroxyisobutyrate dehydrogenase, mitochondrial ELISA Kit
E0670Mo 1 Kit
EUR 758.4

Human HIBADH/ 3-hydroxyisobutyrate dehydrogenase, mitochondrial ELISA Kit
E1120Hu 1 Kit
EUR 726

Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E02H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E02H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E02H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E08H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E08H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E08H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV682483 1.0 ug DNA
EUR 818.4

HIBADH Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV682487 1.0 ug DNA
EUR 818.4

HIBADH Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV682488 1.0 ug DNA
EUR 818.4

Human 3-hydroxyisobutyrate dehydrogenase, mitochondrial,HIBADH ELISA kit
YLA2069HU-48T 48T
EUR 435

Human 3-hydroxyisobutyrate dehydrogenase, mitochondrial,HIBADH ELISA kit
YLA2069HU-96T 96T
EUR 562.5

Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E05H1386-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E05H1386-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) ELISA kit
E05H1386-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig 3 hydroxyisobutye dehydrogenase, mitochondrial(HIBADH) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K7081505 3 x 1.0 ug
EUR 451.2

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K0950805 3 x 1.0 ug
EUR 451.2

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K3137905 3 x 1.0 ug
EUR 451.2

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K7081506 1.0 ug DNA
EUR 200.4

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K7081507 1.0 ug DNA
EUR 200.4

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K7081508 1.0 ug DNA
EUR 200.4

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV682484 1.0 ug DNA
EUR 818.4

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV682485 1.0 ug DNA
EUR 888

HIBADH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV682486 1.0 ug DNA
EUR 888

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K0950806 1.0 ug DNA
EUR 200.4

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K0950807 1.0 ug DNA
EUR 200.4

HIBADH sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K0950808 1.0 ug DNA
EUR 200.4

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K3137906 1.0 ug DNA
EUR 200.4

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3137907 1.0 ug DNA
EUR 200.4

Hibadh sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K3137908 1.0 ug DNA
EUR 200.4

CD11b Antibody Antibody
ABD2911 100 ug
EUR 525.6

ASAP1 antibody Antibody
DF8746 200ul
EUR 420

anti- Antibody^Polyclonal antibody control antibody
LSMab09882 100 ug
EUR 525.6

ARHGDIA Antibody / RHOGDI Antibody
F54788-0.08ML 0.08 ml
EUR 165

ARHGDIA Antibody / RHOGDI Antibody
F54788-0.4ML 0.4 ml
EUR 379

Antibody
A1360-500 each Ask for price

Anti-Glycolipid Antibody (AGA) Antibody
20-abx004855
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ly1 Antibody Reactive (LYAR) Antibody
20-abx008109
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody
20-abx123734
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Ly1 Antibody Reactive (LYAR) Antibody
20-abx014333
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody
abx033330-400ul 400 ul
EUR 627.6

Ly1 Antibody Reactive (LYAR) Antibody
abx033330-80l 80 µl
EUR 343.2

Anti-Glycolipid Antibody (AGA) Antibody
abx036399-100ug 100 ug
EUR 469.2

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319900
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319905
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody
abx230204-100ug 100 ug
EUR 577.2

Ly1 Antibody Reactive (LYAR) Antibody
20-abx324434
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody
20-abx311665
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody
abx234901-100ug 100 ug
EUR 661.2

Anti-Anti-SEPT6 antibody antibody
STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody
STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody
STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody
STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody
STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody
STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody
STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody
STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody
STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody
STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody
STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody
STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody
STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody
STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody
STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody
STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody
STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody
STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody
STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody
STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody
STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody
STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

CLCN5 Antibody / CIC-5 antibody
RQ6462 100ug
EUR 419
Description: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody
48169-100ul 100ul
EUR 399.6

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody
48169-50ul 50ul
EUR 286.8

Anti CD22 Antibody: CD22 Monoclonal Antibody
065-A-01mg 0,1 mg
EUR 321
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody
065-A-1000ug 1000 ug
EUR 1539
Description: anti-CD22 monoclonal antibody

Antibody Pair to ApoA-V antibody
10R-1876 100 ul
EUR 781.2
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody

Ly1 Antibody Reactive Homolog (LYAR) Antibody
20-abx103034
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody
20-abx103035
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody
20-abx103036
  • EUR 577.20
  • EUR 159.60
  • EUR 1696.80
  • EUR 794.40
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Now we have screened, in FRT cells expressing the 3849+10 kb C-to-T splicing mutation, ~30 2′-O-Methyl-modified phosphorothioate ASOs, focused to forestall the popularity and inclusion of a cryptic exon generated because of the mutation. The impact of extremely potent ASO candidates on the splicing sample, protein maturation and CFTR operate was additional analyzed in nicely differentiated main human nasal and bronchial epithelial cells, derived from sufferers carrying at the least one 3849+10 kb C-to-T allele.

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